The subgenus of the genus is one of the most species-rich groups in the family Tipulidae. Here, we present the first mitochondrial genome of the subgenus The nearly complete mitochondrial genome of Savchenko, 1960 (Genbank accession number: OM287601) was 16083 bp in length and consisted of 13 PCGs, 22 tRNA and two rRNA genes. The phylogenetic the tree of family Tipulidae was reconstructed based on 13 PCGs sequences using the maximum likelihood method. The result strongly supported the monophyly of the family Tipulidae. The subgenus is indicated as the sister group of subgenera and .
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http://dx.doi.org/10.1080/23802359.2023.2172975 | DOI Listing |
J Gerontol A Biol Sci Med Sci
January 2025
Department of Joint Surgery, HongHui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Background: Mitochondrial dysfunction has been demonstrated to be an important hallmark of sarcopenia, yet its specific mechanism remains obscure. In this study, mitochondrial-related genes were used as instrumental variables to proxy for mitochondrial dysfunction, and summary data for sarcopenia-related traits were used as outcomes to examine their genetic association.
Methods: A total of 1,136 mitochondrial-related genes from the human MitoCarta3.
Nat Med
January 2025
Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.
Genetic diagnosis of rare diseases requires accurate identification and interpretation of genomic variants. Clinical and molecular scientists from 37 expert centers across Europe created the Solve-Rare Diseases Consortium (Solve-RD) resource, encompassing clinical, pedigree and genomic rare-disease data (94.5% exomes, 5.
View Article and Find Full Text PDFCancer Med
January 2025
Department of Respiratory Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, People's Republic of China.
Background: Lung adenocarcinoma (LUAD) exhibits molecular heterogeneity, with mitochondrial damage affecting progression. The relationship between mitochondrial damage and immune infiltration, and Weighted Gene Co-expression Network Analysis (WGCNA)-derived biomarkers for LUAD classification and prognosis, remains unexplored.
Aims: The objective of our research is to identify gene modules closely related to the clinical stages of LUAD using the WGCNA method.
Wellcome Open Res
November 2024
UK Centre for Ecology & Hydrology, Wallingford, England, UK.
We present a genome assembly from an individual male (Poplar Grey moth; Arthropoda; Insecta; Lepidoptera; Noctuidae). The genome sequence has a total length of 424.20 megabases.
View Article and Find Full Text PDFGenet Med Open
March 2024
Department of Pathology, Stanford University, Stanford, CA.
The number of human disease genes has dramatically increased over the past decade, largely fueled by ongoing advances in sequencing technologies. In parallel, the number of available clinical genetic tests has also increased, including the utilization of exome sequencing for undiagnosed diseases. Although most clinical sequencing tests have been centered on enrichment-based multigene panels and exome sequencing, the continued improvements in performance and throughput of genome sequencing suggest that this technology is emerging as a potential platform for routine clinical genetic testing.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!