AI Article Synopsis
- Liver cirrhosis leads to over 1.2 million deaths each year, particularly affecting patients with decompensated cirrhosis who experience a poor quality of life, making nurse-led outpatient care a critical recommendation for managing this condition.
- A systematic review of studies, which included 16 controlled and prospective trials with a total of 1,224 participants, assessed the effects of nurse-assisted follow-up on patients with liver cirrhosis, focusing on their mortality and readmission rates.
- While all studies showed some improvement in health outcomes through various nursing interventions, the overall quality of evidence was moderate to low, and no single intervention type was definitively proven most effective.
Article Abstract
Background And Objective: Liver cirrhosis represents a considerable health burden and causes 1.2 million deaths annually. Patients with decompensated liver cirrhosis have a poor prognosis and severely reduced health-related quality of life. Nurse-led outpatient care has proven safe and feasible for several chronic diseases and engaging nurses in the outpatient care of patients with liver cirrhosis has been recommended. At the decompensated stage, the treatment and nursing care are directed at specific complications, educational support, and guidance concerning preventive measures and signs of decompensation. This review aimed to assess the effects of nurse-assisted follow-up after admission with decompensation in patients with liver cirrhosis from all causes.
Method: A systematic search was conducted through February 2022. Studies were eligible for inclusion if i) they assessed adult patients diagnosed with liver cirrhosis that had been admitted with one or more complications to liver cirrhosis and ii) if nurse-assisted follow-up, including nurse-assisted multidisciplinary interventions, was described in the manuscript. Randomized clinical trials were prioritized, but controlled trials and prospective cohort studies with the intervention were also included. Primary outcomes were mortality and readmission, but secondary subjective outcomes were also assessed.
Results And Conclusion: We included eleven controlled studies and five prospective studies with a historical control group comprising 1224 participants. Overall, the studies were of moderate to low quality, and heterogeneity across studies was substantial. In a descriptive summary, the 16 studies were divided into three main types of interventions: educational interventions, case management, and standardized hospital follow-up. We saw a significant improvement across all types of studies on several parameters, but currently, no data support a specific type of nurse-assisted, post-discharge intervention. Controlled trials with a predefined intervention evaluating clinically- and practice-relevant endpoints in a real-life, patient-oriented setting are highly warranted.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910708 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0278545 | PLOS |
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