AI Article Synopsis
- - Hepatic small vessel neoplasia (HSVN) is a newly identified liver hemangioma with unclear cancer risk, mostly found in asymptomatic patients.
- - Budd-Chiari syndrome (BCS) is a rare condition that leads to liver venous blockage and has been linked to benign liver nodules, but no prior cases have associated it with HSVN.
- - In this case study, a patient diagnosed with BCS 13 years earlier had liver nodules that were later confirmed as multifocal HSVN at autopsy, highlighting the need to examine imaging changes and the potential link between BCS and HSVN.
Article Abstract
Hepatic small vessel neoplasia (HSVN) is a recently recognized hemangioma of the liver with uncertain malignant potential. Almost all the patients are asymptomatic. Budd-Chiari syndrome (BCS) is a rare disorder characterized by noncardiogenic hepatic venous outflow obstruction. Benign hepatocellular nodules have been acknowledged for a long time in the liver with the chronic BCS. However, there has been no case report of BCS associated with HSVN. The patient was diagnosed with BCS 13 years ago. The imaging test initially displayed multiple hepatic nodules that were suspected of benign hepatocellular nodules. They gradually increased in size and number in the course of the disease. At an autopsy, these nodules were confirmed to be multifocal HSVN. The tumor of the present case could not be proved to have GNAQ and GNQ14 mutations. We describe the case focusing on the chronological imaging changes and discuss on the relationship between BCS and HSVN.
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| http://dx.doi.org/10.1007/s00428-023-03505-w | DOI Listing |
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