Herein, a nickel catalysis system for desulfonylative C(sp)-C(sp) reductive cross-coupling reactions of aryl sulfone derivatives with a range of aryl bromides has been established to form diverse biaryl compounds. The complex Ar-Ni(II)-SOCF bearing a phosphine ligand through oxidative addition of aryl sulfone to Ni(0) species was isolated and confirmed by an X-ray, which provides solid evidence for the understanding of the C(Ar)-SO bond activation and reaction mechanism.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.3c00185 | DOI Listing |
Publication Analysis
Top Keywords
reductive cross-coupling
8
aryl bromides
8
aryl sulfone
8
aryl
5
nickel-catalyzed desulfonylative
4
desulfonylative reductive
4
cross-coupling aryl
4
aryl sulfones
4
sulfones aryl
4
bromides nickel
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!