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Bionanotechnology research has surged to the forefront of scientific innovation, propelling the exploration of cutting-edge technologies and interdisciplinary collaboration. Biomimicry, which harnesses nature's ingenuity, drives the development of novel research-based solutions in diverse fields such as vaccines, medicine, and biomedical devices. Nature's role is becoming increasingly pivotal in addressing complex challenges related to environmental conservation, human health, and pandemic preparedness, including those posed by SARS-CoV-2 and other emerging pathogens.

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Nature continually refines its processes for optimal efficiency, especially within biological systems. This article explores the collaborative efforts of researchers worldwide, aiming to mimic nature's efficiency by developing smarter and more effective nanoscale technologies and biomaterials. Recent advancements highlight progress and prospects in leveraging engineered nucleic acids and proteins for specific tasks, drawing inspiration from natural functions.

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Extracellular vesicles-powered immunotherapy: Unleashing the potential for safer and more effective cancer treatment.

Arch Biochem Biophys

June 2024

Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute Lucknow, India; Academy of Scientific and Innovation Research (AcSIR), Ghaziabad, 201002, U.P., India. Electronic address:

Cancer treatment has seen significant advancements with the introduction of Onco-immunotherapies (OIMTs). Although some of these therapies have received approval for use, others are either undergoing testing or are still in the early stages of development. Challenges persist in making immunotherapy widely applicable to cancer treatment.

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Artificial Feeding Systems for Vector-Borne Disease Studies.

Biology (Basel)

March 2024

Department of Tropical Medicine and Infectious Disease, Tulane University, New Orleans, LA 70112, USA.

This review examines the advancements and methodologies of artificial feeding systems for the study of vector-borne diseases, offering a critical assessment of their development, advantages, and limitations relative to traditional live host models. It underscores the ethical considerations and practical benefits of such systems, including minimizing the use of live animals and enhancing experimental consistency. Various artificial feeding techniques are detailed, including membrane feeding, capillary feeding, and the utilization of engineered biocompatible materials, with their respective applications, efficacy, and the challenges encountered with their use also being outlined.

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The spleen is an important mediator of both adaptive and innate immunity. As such, attempts to modulate the immune response provided by the spleen may be conducive to improved outcomes for numerous diseases throughout the body. Here, biomimicry is used to rationally design nanomaterials capable of splenic retention and immunomodulation for the treatment of disease in a distant organ, the postinfarct heart.

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