Unlabelled: Sinonasal teratocarcinosarcoma (SNTCS) is a highly malignant and rare tumour characterised by a complex admixture of teratomatous and carcinosarcomatous components. In the head and neck area, it almost exclusively occurs in the sinonasal cavities; however, rare instances of nasopharyngeal and oral cavity involvement have been reported, with fewer than 100 cases reported in the literature.
Contribution: The contributed case involves the correlative CT, MRI and histopathology of a sinonasal teratocarcinosarcoma with intracranial involvement.
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| http://dx.doi.org/10.4102/sajr.v27i1.2548 | DOI Listing |
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Teratocarcinosarcoma of the nasal cavity: challenges in the clinico-pathologic perspectives.
Eur Arch Otorhinolaryngol
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Department of Otorhinolaryngology and Head-Neck Surgery, All India Institute of Medical Sciences, Kalyani, NH-34 Connector, Basantapur, Saguna, Nadia, Kalyani, West Bengal, 741245, India.
Objective: Clinicopathologic illustration of sinonasal teratocarcinosarcoma (SNTCS) in a middle-aged man, highlighting the difficulties and challenges encountered during surgical intervention, histopathologic diagnosis, and its overall management.
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Results: A 40-year-old man having recurrent epistaxis for three months presented with a dark-colored protruding polypoid nasal mass.
Sinonasal Teratocarcinosarcoma in a Thirty Five Year Old Male Patient: A Case Report from a Regional Cancer Institute of Eastern India.
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December 2024
Department of Histopathology, Chittaranjan National Cancer Institute, Second campus, New Town, Kolkata India.
Sinonasal Teratocarcinosarcoma is one of the rarest tumours specific for sinonasal tract with a handful of reported cases worldwide. This triphasic tumour show differentiation towards carcinosarcomatous component with associated primitive neural component. Here, we report a case of Sinonasal Teratocarcinosarcoma in a thirty five year old male patient from a regional cancer Institute of Eastern India with thorough review of literature.
View Article and Find Full Text PDFSinonasal teratocarcinosarcoma involving the nasal cavity, unilateral paranasal sinuses, and intracranial invasion: A case report.
World J Clin Cases
September 2024
Department of Radiology, 900 Hospital of Joint Logistics Support Force, Fuzhou 350025, Fujian Province, China.
Background: Sinonasal teratocarcinosarcoma (SNTCS) is a rare and highly invasive neoplasm originating from the nasal cavity and sinuses. Typically, it exhibits an invasive behavior towards adjacent structures; however, in exceptional instances, it may infiltrate the intracranial compartment. Due to the tumor's rarity and lack of distinctive features on computed tomography (CT) and magnetic resonance imaging (MRI) images, SNTCS is often misdiagnosed.
View Article and Find Full Text PDFSinonasal Malignancy Following Cranial Irradiation: A Scoping Review and Case Report of Sinonasal Teratocarcinosarcoma.
J Neurol Surg Rep
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Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.
Radiation therapy is a mainstay of treatment for brain tumors, but delayed complications include secondary malignancy which may occur months to years after treatment completion. We reviewed the medical records of a 41-year-old female treated with 60 Gy of radiation for a recurrent astrocytoma, who 6 years later developed a locally advanced sinonasal teratocarcinosarcoma. We searched MEDLINE, Embase, and Web of Science to conduct a scoping review of biopsy-proven sinonasal malignancy in patients who previously received cranial irradiation for a brain tumor.
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Clin Oncol (R Coll Radiol)
June 2024
Medical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India. Electronic address:
Aims: Sinonasal teratocarcinosarcomas (SNTCS) are rare sinonasal malignancies, the incidence of which is less than 1% of all tumors. There is limited data available on SNTCS's, often as case reports and small case series. The management of SNTCS is complicated because of its location, locally aggressive biology, difficulty in achieving complete resection, and limited data on chemotherapy in these malignancies.
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