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Digital markers of asthma exacerbations: a systematic review.

ERJ Open Res

November 2024

School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland, Aukland, New Zealand.

Background And Objective: With the increase in use of digital technologies, there is growing interest in digital markers, where technology is used to detect early markers of disease deterioration. The aim of this systematic review is to summarise the evidence relating to digital markers of asthma exacerbations.

Methods: A systematic search of the following databases was conducted, using key search terms relating to asthma, digital and exacerbations: Ovid MEDLINE, EMBASE, Psycinfo, Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled Trials.

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Article Synopsis
  • * These technologies pave the way for decentralized clinical trials, allowing for a more inclusive study population, reduced costs, and faster access to new treatments.
  • * The discussion includes the use of digital endpoints, different trial designs, a specific example of a fully decentralized asthma trial, and examines the pros and cons of these methods from various perspectives (clinicians, patients, and regulators).
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Article Synopsis
  • Over-reliance on Short-Acting Beta-Agonists (SABA) leads to poor asthma control and increased risks of exacerbations and death, highlighting the need for intervention.
  • The study evaluated the Reliever Reliance Test (RRT), a tool designed to help patients self-assess and change their behavior related to SABA usage.
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is a medical education podcast that utilizes an innovative approach to undergraduate medical education by engaging medical students as teachers. This report describes the podcast, the benefits of engaging students as teachers, and future directions to improve the platform and formally study its impact.

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