Physiology Reconfigured: How Does Bariatric Surgery Lead to Diabetes Remission?

Endocrinol Metab Clin North Am

Integrative Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, LA 70808, USA. Electronic address:

Published: March 2023

Bariatric surgery improves glucose homeostasis and glycemic control in patients with type 2 diabetes. Over the past 20 years, a breadth of studies has been conducted in humans and rodents aimed to identify the regulatory nodes responsible for surgical remission of type 2 diabetes. The review herein discusses central mechanisms of type 2 diabetes remission associated with weight loss and surgical modification of the gastrointestinal tract.

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http://dx.doi.org/10.1016/j.ecl.2022.06.003DOI Listing

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