AI Article Synopsis
- - Patients aged 70 and older make up a significant part of the COVID-19 ICU population in the Netherlands, with high mortality rates, prompting a study to compare their outcomes with those of similar patients suffering from bacterial and other viral pneumonias.
- - The study analyzed data from over 11,000 patients, finding that those admitted for COVID-19 had ICU and hospital mortality rates of 39.7% and 47.6%, respectively, which are significantly higher than the rates for those admitted for bacterial or other viral pneumonia.
- - Results indicate that even after considering factors like age, health conditions, and ICU capacity, COVID-19 remains a more severe illness for patients aged 70 and older compared to bacterial
Article Abstract
Background: Patients over 70 years old represent a substantial proportion of the COVID-19 ICU population and their mortality rates are high. The aim of this study is to describe the outcomes of patients ≥70 years old admitted to Dutch ICUs with COVID-19, compared to patients ≥70 years old admitted to the ICU for bacterial and other viral pneumonias, with adjustments for age, comorbidities, severity of illness, and ICU occupancy rate.
Methods: Retrospective cohort study including patients ≥70 years old admitted to Dutch ICUs, comparing patients admitted with COVID-19 from March 1st 2020 to January 1st 2022 with patients ≥70 years old admitted because of a bacterial and other viral pneumonia, both divided in a historical (i.e., January 1st 2017 to January 1st 2020) and current cohort (i.e., March 1st 2020 to January 1st 2022). Primary outcome is hospital mortality.
Results: 11,525 unique patients ≥70 years old admitted to Dutch ICUs were included; 5094 with COVID-19, 5334 with a bacterial pneumonia, and 1312 with another viral pneumonia. ICU-mortality and in-hospital mortality rates of the patients ≥70 years old admitted with COVID-19 were 39.7% and 47.6% respectively. ICU- and hospital mortality rates of the patients who were admitted in the same or in an historical time period with a bacterial pneumonia or other viral pneumonias were considerably lower (19.5% and 28.6% for patients with a bacterial pneumonia in the historical cohort and 19.1% and 28.8% in the same period, for the patients with other viral pneumonias 20.7% and 28.9%, and 22.7% and 31.8% respectively, all p < 0.001). Differences persisted after correction for several clinical characteristics and ICU occupancy rate.
Conclusions: In ICU-patients ≥70 years old, COVID-19 is more severe compared to bacterial or viral pneumonia.
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| http://dx.doi.org/10.1111/jgs.18220 | DOI Listing |
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