Background: Injuries and violence share many of the same risk and protective factors, which are rooted in the social determinants of health (SDOH) and the social determinants of equity. Addressing shared risk and protective factors (SRPFs)-common factors that make it more or less likely that a population will experience injuries or violence-is critical prevention efforts. The Safe States Alliance created the Connections Lab-a suite of web-based resources to help injury and violence prevention public health practitioners and their partners understand, describe, implement and evaluate SRPF approaches.
Design: A mixed-methods approach using the Diffusion of Innovation Theory assessed how the Connections Lab influenced users' knowledge, abilities and work related to SRPF approaches. A web-based survey was administered to 234 participants in April-May 2021. Semistructured virtual group discussions were conducted with a subset of 15 survey respondents who volunteered to participate.
Results: The case study revealed three key findings. The Connections Lab: was diffused among practitioners across sectors within and outside of public health; it increased practitioners' perceived proficiency across 10 skill sets related to describing, planning, implementing and evaluating SRPF approaches; and it increased understanding of the importance of upstream and structural drivers of injuries and violence.
Conclusion: The Connections Lab was a critical first step to expand the definition of SRPF approaches, connect SRPFs to concepts of equity and the SDOH, and provide strategies for engaging partners in public health and across other sectors in SRPF approaches.
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http://dx.doi.org/10.1136/ip-2022-044804 | DOI Listing |
J Mater Chem B
January 2025
Department of Chemistry, Amrita School of Physical Sciences Coimbatore, Amrita Vishwa Vidyapeetham, India.
We investigated the and uses of pamoic acid functionalized gold nanoparticles (PA@AuNPs), with a focus on determining their safety and potential toxicity in living beings. To test this theory, the bacterial interaction of PA@AuNPs was studied using , , and cultures, as well as the inhibition of the bovine serum albumin (BSA) protein. The real-time polymerase chain reaction (RT-PCR) is used to measure the expression of target genes.
View Article and Find Full Text PDFWorld Psychiatry
February 2025
Department of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.
This is the first bottom-up review of the lived experience of postpartum depression and psychosis in women. The study has been co-designed, co-conducted and co-written by experts by experience and academics, drawing on first-person accounts within and outside the medical field. The material initially identified was shared with all participants in a cloud-based system, discussed across the research team, and enriched by phenomenological insights.
View Article and Find Full Text PDFBMC Genom Data
January 2025
Department of Management Information Systems, National Chung Hsing University, Taichung, 402, Taiwan.
Background: miRNAs (microRNAs) are endogenous RNAs with lengths of 18 to 24 nucleotides and play critical roles in gene regulation and disease progression. Although traditional wet-lab experiments provide direct evidence for miRNA-disease associations, they are often time-consuming and complicated to analyze by current bioinformatics tools. In recent years, machine learning (ML) and deep learning (DL) techniques are powerful tools to analyze large-scale biological data.
View Article and Find Full Text PDFSci Rep
January 2025
College of Computing and Information Technology, University of Bisha, Bisha, Bisha, 61922, Saudi Arabia.
Smart devices are enabled via the Internet of Things (IoT) and are connected in an uninterrupted world. These connected devices pose a challenge to cybersecurity systems due attacks in network communications. Such attacks have continued to threaten the operation of systems and end-users.
View Article and Find Full Text PDFEBioMedicine
January 2025
MGH Biostatistics Center, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:
Background: The ovarian cancer (OC) preclinical detectable phase (PCDP), defined as the interval during which cancer is detectable prior to clinical diagnosis, remains poorly characterised. We report exploratory analyses from the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
Methods: In UKCTOCS between Apr-2001 and Sep-2005, 101,314 postmenopausal women were randomised to no screening (NS) and 50,625 to annual multimodal screening (MMS) (until Dec-2011) using serum CA-125 interpreted by the Risk of Ovarian Cancer Algorithm (ROCA).
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