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Application of Nanomaterials Targeting Immune Cells in the Treatment of Chronic Inflammation.
Int J Nanomedicine
December 2024
Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, People's Republic of China.
Article Synopsis
- Chronic inflammation is linked to various diseases and is characterized by prolonged immune cell activation, resulting in tissue damage.
- Despite the effectiveness of current anti-inflammatory medications, they often have side effects due to non-specific targeting.
- Nanoparticle drug delivery shows promise for targeted therapy in inflammation, but improvements are needed to specifically target different immune cell types for enhanced therapeutic effects.
Comparison of Single and Multiple Intratracheal Administrations for Pulmonary Toxic Responses of Multi-Walled Carbon Nanotubes in Rats.
Nanomaterials (Basel)
December 2024
Former Japan Bioassay Research Center, Hadano 257-0015, Kanagawa, Japan.
The purpose of the present study is to contribute to the establishment of a standard method for evaluating the adverse effects of nanomaterials by intratracheal administration. Low and high doses of multi-walled carbon nanotubes (MWCNTs) were administered to rats in a single administration or the same final dose as the single administration but divided over four administrations. Bronchoalveolar lavage examination on day 14 showed an inflammatory reaction and cytotoxicity in the lung, generally greater at the higher dose, and tending to be greater in the rats with four administrations at both the low and high doses.
View Article and Find Full Text PDFThe "Pfizer Boob Job": A Case of Unexplained Gigantomastia.
Plast Reconstr Surg Glob Open
December 2024
From the Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
True parenchymal breast changes following COVID-19 vaccination are exceedingly rare. Equally rare are incidences of pseudoangiomatous stromal hyperplasia (PASH)-associated gigantomastia. The patient in this case report presented with both occurrences and experienced massive breast enlargement 1 week postadministration of the Pfizer/BioNTech COVID-19 vaccine, which worsened after her second dose.
View Article and Find Full Text PDF[Analysis of morphological characteristics of laryngeal tuberculosis based on electronic laryngoscopy and image-enhanced endoscopy].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
December 2024
Department of Otorhinolaryngology, the Second Affiliated Hospital Zhejiang University School of Medicne, Hangzhou310000, China.
To explore and summarize the morphological features of laryngeal tuberculosis under electronic laryngoscopy and image-enhanced endoscopy (i-scan). A retrospective analysis was conducted on the data of 31 patients diagnosed with laryngeal tuberculosis at the Second Affiliated Hospital of Zhejiang University School of Medicine from January 2014 to June 2024, encompassing the morphological features of electronic laryngoscopy and i-scan endoscopy, histopathological features, and supplementary clinical examination results. Descriptive statistical methods were employed for the analysis.
View Article and Find Full Text PDFDeep Fungal Infections of Skin and Role of Histopathology in Diagnosis.
Indian J Dermatol
October 2024
Department of Dermatology, Institute of Child Health, Kolkata, India.
Introduction: Deep mycoses acquired by penetrating trauma to the skin can have varied and sometimes atypical morphological presentations resulting in diagnostic dilemmas and delay in treatment onset. Histopathology can be a useful tool in not only diagnosing but also differentiating various deep mycoses.
Aims And Objectives: To observe various morphological presentations and histopathological features of deep fungal infections.
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