Eremomycin, a novel antibiotic belonging to the group of cyclic glycopeptides is produced by an actinomycete designated INA-238. Biosynthesis, isolation, physico-chemical and biological properties of the antibiotic are described. Eremomycin is shown to be close to vancomycin. However, by its chromatographic and electrophoretic mobility, presence of chlorine in the antibiotic molecule and optic characteristics eremomycin differs from vancomycin. Eremomycin is less toxic than vancomycin whereas its chemotherapeutic activity in treatment of infections caused by gram-positive organisms is higher.

Download full-text PDF

Source

Publication Analysis

Top Keywords

[eremomycin--a antibiotic
4
antibiotic cyclic
4
cyclic glycopeptide
4
glycopeptide group]
4
eremomycin
4
group] eremomycin
4
eremomycin novel
4
novel antibiotic
4
antibiotic belonging
4
belonging group
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!