AI Article Synopsis
- - This research presents a new method that reduces isocyanates to formamide derivatives without using transition metals, relying instead on pinacolborane (HBpin) for hydrogenation.
- - A magnesium complex with a specialized ligand (bis(phosphino)carbazole) acts as a catalyst, ensuring the process is efficient and controlled.
- - The method successfully applies to a wide range of substrates, resulting in a selective generation of -boryl formamides.
Article Abstract
This work describes a transition metal-free methodology involving an efficient and controlled reduction of isocyanates to only formamide derivatives using pinacolborane (HBpin) as the hydrogenating agent and a bis(phosphino)carbazole ligand stabilized magnesium methyl complex (1) as the catalyst. A large number of substrates undergo selective hydroboration and give exclusively -boryl formamides.
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| http://dx.doi.org/10.1039/d3cc00036b | DOI Listing |
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