Adolescent extra-truncal progressive macular hypomelanosis.

Pediatr Dermatol

Division of Dermatology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States.

Published: July 2023

Two adolescent females presented to outpatient clinic with isolated, non-scaly, asymptomatic hypopigmented macules and patches on the arm(s). Both cases had Wood's lamp exams notable for extralesional punctiform coral-red perifollicular fluorescence on the back and faint intralesional enhancement. In one case, biopsy was performed and deemed consistent with progressive macular hypomelanosis. The patient had complete response to antimicrobial therapy and sun exposure.

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.15252DOI Listing

Publication Analysis

Top Keywords

progressive macular
8
macular hypomelanosis
8
adolescent extra-truncal
4
extra-truncal progressive
4
hypomelanosis adolescent
4
adolescent females
4
females presented
4
presented outpatient
4
outpatient clinic
4
clinic isolated
4

Similar Publications

Evaluating Choroidal Vascular Changes in Young Adults With High Myopia Utilizing Swept source optical coherence tomography angiography.

Photodiagnosis Photodyn Ther

January 2025

Southwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing 400038, China.; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, China; Jinfeng Laboratory, Chongqing, China. Electronic address:

Purpose: Utilizing Swept source optical coherence tomography angiography (SS-OCTA) investigates the changes in the vascular characteristics of the choriocapillaris and larger vascular layers, including Sattler's and Haller's layers, in the macular region of young myopia patients, in order to to Enhance our comprehension of the underlying mechanisms of the pathogenesis of myopia.

Methods: A retrospective analysis was performed on 103 young adults (154 eyes) that underwent SS-OCTA. Axial lengths (AL) were measured, 64 eyes with AL < 26.

View Article and Find Full Text PDF

Purpose: We describe an atypical presentation of an 11-year-old female with enhanced S-cone syndrome (ESCS).

Methods: Case report. The patient underwent a thorough ophthalmic examination and investigations such as colour fundus photography, optical coherence tomography, fundus autofluorescence, fluorescein and indocyanine angiography, an electroretinogram and genetic testing.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Ophthalmology, Myongji Hospital, Hanyang University College of Medicine, Goyang, Korea, Republic of (South).

Background: Spectrum Domain-Optical Coherence Tomography (SD-OCT) is a non-invasive technology that acquires cross-sectional images of retinal structures allowing neural fundus integrity assessment. Macular thickness and retinal nerve fiber layer (RNFL) thickness measured by an SD-OCT have been used as a indicator of Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI). However which portion of retinal RNFL is the most sensitive area among normal control, aMCI and AD is not clear yet.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Parkland, FL, USA.

Background: The early detection of neurologic damage at the microscopic level when the disease is subclinical would facilitate intervention preventing progression or potentially reversing the condition. The early determination of drug efficacy could shorten the length of drug studies, thereby reducing research costs. The eye is the only place in the body where an artery, vein, and nerve can be directly visualized The nerve fiber layer of the retina is an outgrowth of the brain.

View Article and Find Full Text PDF

Technology and Dementia Preconference.

Alzheimers Dement

December 2024

Parkland, FL, USA.

Background: The early detection of neurologic damage at the microscopic level when the disease is subclinical would facilitate intervention preventing progression or potentially reversing the condition. The early determination of drug efficacy could shorten the length of drug studies, thereby reducing research costs. The eye is the only place in the body where an artery, vein, and nerve can be directly visualized The nerve fiber layer of the retina is an outgrowth of the brain.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!