Benign schwannoma is a slow growing encapsulated tumor arising from the sheath of Schwann, The majority had extra-cranial localization. We report in this review three cases of a rare extra cranial localization of benign schwannoma in the trachea, frontal sinus and intraparotid facial nerve. The first case diagnosed in a 10-years-old boy, presented with a painless, slow growing mass evolving for three years in the left parotidic region, total conservative parotidectomy was done. The second case concerned a 38-years-old, was admitted to the emergency department with acute inspiratory dyspnea, endoscopic exploration revealed a polylobed tracheal tumor, complete tumor excision was done endoscopically. The third case was about a 33 years old patient, presented a gradually enlarging frontal swelling associated with headache and left nasal obstruction, the endoscopic examination revealed a gray pinkish, smooth and firm soft tissue mass occupying the entire left nasal cavity, CT scan and MRI were requested to assess the characteristics and extent of the tumor, The surgical intervention combined two approaches: trans facial through a mid-frontal incision, and endonasal one. Histopathological examination confirmed the diagnosis of benign schwannoma in all these cases.
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http://dx.doi.org/10.1007/s12070-021-02878-1 | DOI Listing |
Indian J Otolaryngol Head Neck Surg
January 2025
Department of Otohinolaryngology & Head- Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.
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Department of Infectious diseases, University of Louisville Hospital, Louisville, USA.
Introduction: Invasive pulmonary aspergillosis (IPA) is typically associated with immunocompromised patients, but rare occurrences have been documented in immunocompetent individuals. This presents diagnostic and therapeutic challenges due to atypical presentations and less apparent risk factors.
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Cureus
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Department of Neurosurgery, Unidade Local de Saude (ULS) Santa Maria, Lisbon, PRT.
Schwannomas are nerve sheath tumors arising from Schwann cells. Schwannomas of the intercostal nerve are extremely rare, with limited published literature. These tumors are generally regarded as benign asymptomatic.
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Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
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February 2025
UCL Ear Institute, University College London, 332 Gray's Inn Road, London, WC1X 8EE, UK. Electronic address:
NF2-related schwannomatosis (NF2-SWN, formerly known as neurofibromatosis type 2) is an autosomal dominant disorder associated with the growth of bilateral schwannomas on the cochleo-vestibular nerves and meningiomas. NF2-SWN is caused by pathogenic variations in the NF2, moesin-ezrin-radixin-like (MERLIN) tumour suppressor gene. The mostly benign tumours can cause progressive sensorineural hearing loss, tinnitus and balance dysfunction.
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