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CM-Pf deep brain stimulation in polyneuromodulation for epilepsy.
Epileptic Disord
October 2024
Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA.
Article Synopsis
- Neuromodulation is a promising option for drug-resistant epilepsy, showcasing case studies involving patients with multiple deep brain stimulators and their responses.
- A thorough review of literature indicates that combining vagus nerve stimulation, responsive neurostimulation, and deep brain stimulation is increasingly reported for treating these patients.
- A notable case is presented where a 28-year-old male with drug-resistant focal epilepsy achieved a 75% seizure reduction through the centromedian-parafascicular deep brain stimulation after inadequate results from previous treatments, emphasizing the safety and effectiveness of dual-device therapies.
Is thalamic deep brain stimulation synergistic with vagus nerve stimulation in drug-resistant genetic generalized epilepsy?
Epileptic Disord
June 2023
Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA.
Neuromodulation in epilepsy is a proven treatment for people with drug-resistant focal epilepsy. Dual device therapies are increasingly utilized in people with drug-resistant epilepsy. Vagus nerve stimulation (VNS) and deep brain stimulation (DBS) target the thalamus involving the primary neurobiological network in patients with genetic generalized epilepsy (GGE).
View Article and Find Full Text PDFObjective: The aim of this study was to assess the safety and efficacy of combined active responsive neurostimulation (RNS) and vagus nerve stimulation (VNS) therapies in pediatric patients with drug-resistant epilepsy.
Methods: A single-center retrospective chart review was conducted on pediatric patients implanted with the RNS System with a concomitant active VNS System (VNS+RNS) between 2015 and 2021. Patients with at least 1 month of overlapping concomitant VNS and RNS treatment were included.
Response to: Dual Device Neuromodulation Can Be Effective in Drug Resistant Generalized Epilepsies.
Neuromodulation
February 2023
São Paulo Epilepsy Clinic, São Paulo, São Paulo, Brazil.
Dual-Device Neuromodulation Can Be Effective in Drug-Resistant Generalized Epilepsies.
Neuromodulation
February 2023
Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.
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