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Criticality is Associated with Future Psychotherapy Response in Patients with Post-Traumatic Stress Disorder-A Pilot Study.
Chronic Stress (Thousand Oaks)
January 2025
Brain Research and Innovation Centre, Ministry of Defence, Utrecht, the Netherlands.
Background: Trauma-focused psychotherapy is treatment of choice for post-traumatic stress disorder (PTSD). However, about half of patients do not respond. Recently, there is increased interest in brain criticality, which assesses the phase transition between order and disorder in brain activity.
View Article and Find Full Text PDFEarly life microbial succession in the gut follows common patterns in humans across the globe.
Nat Commun
January 2025
Department of Biological Sciences, Wellesley College, Wellesley, MA, USA.
Characterizing the dynamics of microbial community succession in the infant gut microbiome is crucial for understanding child health and development, but no normative model currently exists. Here, we estimate child age using gut microbial taxonomic relative abundances from metagenomes, with high temporal resolution (±3 months) for the first 1.5 years of life.
View Article and Find Full Text PDFOversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis.
Elife
January 2025
Cell Biology, Hospital for Sick Children, Toronto, Canada.
Proliferating animal cells maintain a stable size distribution over generations despite fluctuations in cell growth and division size. Previously, we showed that cell size control involves both cell size checkpoints, which delay cell cycle progression in small cells, and size-dependent regulation of mass accumulation rates (Ginzberg et al., 2018).
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