Aconitum heterophyllum is a rare perennial herb from Kashmir Himalayas. Due to its threatened status and dependence on its environment, the plant was examined for any potential endophytes, which is of utmost importance for bioprospection. In the current study, endophytic fungal diversity associated with A. heterophyllum was examined, and 328 fungal isolates were found in the plant's leaf, stem, and root tissues. Twelve (12) endophytic fungal species were identified utilizing, molecular analysis of the nuclear ribosomal DNA Internal Transcribes Spacer (ITS), rLSU, and rSSU sequences. Maximum likelihood analysis was used to determine the phylogenetic connection between each isolate. The genera Arthrinium, Chaetomium, Purpureocillium, Alternaria, Penicillium, Aspergillus, Cladosporium, and Bjerkandera species dominated the ascomycete and basidiomycete fungal endophytes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10123-023-00331-7 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Airways Relaxant and Antiasthmatic Activity of Aconitum heterophyllum Wall ex Royle. Roots: A Mechanistic Insight.
Cell Biochem Biophys
September 2024
Department of Pharmacy, Banasthali Vidyapith, Banasthali, Rajasthan, India.
Aconitum heterophyllum Wall ex Royle. (Ranunculaceae) is a traditional medicinal herb that has shown extensive pharmacological potential to treat cough, diarrhea, and infectious diseases but no scientific evidence is available to validate its antiasthmatic potential. In this study, we have investigated the tracheal relaxation and antiasthmatic activity of the selected bioactive fraction of A.
View Article and Find Full Text PDFInsights into Metabolites Profiling and Pharmacological Investigation of wall ex. Royle Stem through Experimental and Bioinformatics Techniques.
ACS Omega
June 2024
Department of Medicinal Chemistry, College of Pharmacy, Analytical Biochemistry Shared Resource of the Masonic Cancer Center, CCRB, University of Minnesota, Minneapolis, Minnesota 55455, United States.
The genus is a leading source of a wide range of structurally diverse metabolites with significant pharmacological implications. The present study investigated metabolite profiling, pharmacological investigation, anticancer potential, and molecular docking analysis of the stem part of (AHS). The metabolite profiling of the AHS extract was experimentally examined using LC-MS/MS-orbitrap in both modes (ESI/ESI) and GC-MS in EI mode.
View Article and Find Full Text PDFExploring DNA barcode for accurate identification of threatened Aconitum L. species from Western Himalaya.
Mol Biol Rep
January 2024
Biotechnology, Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India.
Background: Aconitum species, belonging to Ranunculaceae, have high medicinal importance but due to their overexploitation come under IUCN (International Union for Conservation of Nature) red list. The precise identification of the Aconitum species is equally important because they are used in herbal formulations. The present study aimed to develop an efficient DNA barcode system for the authentic identification of Aconitum species.
View Article and Find Full Text PDFEthnopharmacologically important highly subsidized Indian medicinal plants: Systematic review on their traditional uses, phytochemistry, pharmacology, quality control, conservation status and future prospective.
J Ethnopharmacol
February 2024
C-H Activation & Phytochemistry Lab, Chemical Technology Division, CSIR-IHBT, Palampur, Himachal Pradesh, 176061, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address:
Article Synopsis
- India has a rich history of using medicinal plants for health, with many traditional practices like Ayurveda, Siddha, and Homeopathy recognizing hundreds of plant species.
- The study aims to give updated information on thirteen selected medicinal plants that the Indian government is encouraging farmers to grow by offering a 75% subsidy on cultivation costs.
- Information was gathered from various online sources and government websites to help understand these plants' uses, benefits, and importance for conservation.
Anti-proliferative potentials of Root Extract in Human Breast cancer (MDA-MB-231) cell lines-Genetic and Antioxidant enzyme approach.
Avicenna J Med Biotechnol
January 2023
Department of Biotechnology Dr M.G.R Educational and Research Institute Maduravoyal, Chennai, Tamil Nadu, India.
Background: One of the most important research activities around the world is the screening of various plant components for novel anticancer medicines. The anticancer activities of were studied in human breast cancer MDA-MB-231 cells in this study. Since tumorigenesis is thought to be the result of a series of progressive gene alterations, including oncogene activation and tumour suppressor gene inactivation, the expression of genes like , and , which are thought to be important in tumorigenesis and cell death, was determined.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!