AI Article Synopsis

  • The study aimed to assess the outcomes of isolated coronary artery bypass grafting (CABG) in patients with or without revascularization of the occluded right coronary artery (RCA).
  • Based on a large European registry, the analysis included 724 patients with RCA occlusion, revealing that one-third did not undergo revascularization, showing variability among medical centers.
  • Results indicated that patients without RCA revascularization had a higher 5-year all-cause mortality rate (17.7%) and an increased risk of major adverse cardiovascular and cerebrovascular events (MACCE) compared to those who had the procedure (24.7% vs. 15.7%).

Article Abstract

Objectives: The aim of the present study was to evaluate the results of isolated coronary artery bypass grafting (CABG) with or without revascularization of the occluded right coronary artery (RCA).

Methods: Patients undergoing isolated CABG were included in a prospective European multicenter registry. Outcomes were adjusted for imbalance in preoperative variables with propensity score matching analysis. Late outcomes were evaluated with Kaplan-Meier's method and competing risk analysis.

Results: Out of 2,948 included in this registry, 724 patients had a total occlusion of the RCA and were the subjects of this analysis. Occluded RCA was not revascularized in 251 (34.7%) patients with significant variability between centers. Among 245 propensity score-matched pairs, patients with and without revascularization of occluded RCA had similar early outcomes. The nonrevascularized RCA group had increased rates of 5-year all-cause mortality (17.7 vs. 11.7%,  = 0.039) compared with patients who had their RCA revascularized. The rates of myocardial infarction and repeat revascularization were only numerically increased but contributed to a significantly higher rate of MACCE (24.7 vs. 15.7%,  = 0.020) at 5 year among patients with nonrevascularized RCA.

Conclusion: In this multicenter study, one-third of totally occluded RCAs was not revascularized during isolated CABG for multivessel coronary artery disease. Failure to revascularize an occluded RCA in these patients increased the risk of all-cause mortality and MACCEs at 5 years.

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Source
http://dx.doi.org/10.1055/s-0043-1761625DOI Listing

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