Microbiota-induced IL-17 production mediates CNS processes and animal behavior. However, its role on the peripheral nervous system (PNS) remains largely unknown. Enamorado et al. demonstrate that commensal-specific Th17 cells are recalled following tissue injury to support local nerve regeneration, a process orchestrated by IL-17 signaling on peripheral neurons.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10967262 | PMC |
| http://dx.doi.org/10.1016/j.cell.2022.12.048 | DOI Listing |
Publication Analysis
Top Keywords
il-17 nerves
4
nerves microbiota-induced
4
microbiota-induced il-17
4
il-17 production
4
production mediates
4
mediates cns
4
cns processes
4
processes animal
4
animal behavior
4
behavior role
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!