AI Article Synopsis
- The study investigates how age affects blood flow patterns in the thoracic aorta, using advanced 4D flow cardiovascular magnetic resonance (CMR) imaging.
- A total of 126 volunteers aged 20-80 were analyzed to establish reference values, focusing on multiple flow parameters across different age groups and both genders.
- Results indicated that older individuals showed distinct differences in flow parameters, particularly in the ascending aorta, which could have implications for understanding cardiovascular health and disease.
Article Abstract
. This study assesses age-related differences of thoracic aorta blood flow profiles and provides age- and sex-specific reference values using 4D flow cardiovascular magnetic resonance (CMR) data.. 126 volunteers (age 20-80 years, female 51%) underwent 4D flow CMR and 12 perpendicular analysis planes in the thoracic aorta were specified. For these planes the following parameters were evaluated: body surface area-adjusted aortic area ('), normalized flow displacement (NFD), the degree of wall parallelism (WPD), the minimal relative cross-sectional area through which 80% of the volume flow passes (A80) and the angle between flow direction and centerline ().. Age-related differences in blood flow parameters were seen in the ascending aorta with higher values for NFD and angle and lower values for WPD and A80 in older subjects. All parameters describing blood flow patterns correlated with the cross-sectional area in the ascending aorta. No relevant sex-differences regarding blood flow profiles were found.. These age- and sex-specific reference values for quantitative parameters describing blood flow within the aorta might help to study the clinical relevance of flow profiles in the future.
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| http://dx.doi.org/10.1088/1361-6579/acb8fd | DOI Listing |
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