Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1515/cclm-2023-0095 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
morphoHeart: A quantitative tool for integrated 3D morphometric analyses of heart and ECM during embryonic development.
PLoS Biol
January 2025
School of Biosciences and Bateson Centre, University of Sheffield, Western Bank, Sheffield, United Kingdom.
Heart development involves the complex structural remodelling of a linear heart tube into an asymmetrically looped and ballooned organ. Previous studies have associated regional expansion of extracellular matrix (ECM) space with tissue morphogenesis during development. We have developed morphoHeart, a 3D tissue segmentation and morphometry software with a user-friendly graphical interface (GUI) that delivers the first integrated 3D visualisation and multiparametric analysis of both heart and ECM morphology in live embryos.
View Article and Find Full Text PDFMarigold: a machine learning-based web app for zebrafish pose tracking.
BMC Bioinformatics
January 2025
Biology Department, University of Massachusetts Amherst, Amherst, MA, USA.
Background: High-throughput behavioral analysis is important for drug discovery, toxicological studies, and the modeling of neurological disorders such as autism and epilepsy. Zebrafish embryos and larvae are ideal for such applications because they are spawned in large clutches, develop rapidly, feature a relatively simple nervous system, and have orthologs to many human disease genes. However, existing software for video-based behavioral analysis can be incompatible with recordings that contain dynamic backgrounds or foreign objects, lack support for multiwell formats, require expensive hardware, and/or demand considerable programming expertise.
View Article and Find Full Text PDFAssessing Readability of Patient Education Materials on Adult-Acquired Buried Penis.
Ann Plast Surg
January 2025
From the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Wisconsin, Madison, WI.
Introduction: Adult-acquired buried penis (AABP) is an increasingly prevalent condition characterized by the penis "buried" in prepubic/suprapubic tissue. AABP affects urinary and sexual function, hygiene, and psychosocial well-being. Because many affected individuals are unfamiliar with the condition or hesitant to seek medical help, accessible, high-quality patient education materials (PEMs) are necessary.
View Article and Find Full Text PDFMetaboLINK is a novel algorithm for unveiling cell-specific metabolic pathways in longitudinal datasets.
Front Neurosci
January 2025
Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX, United States.
Introduction: In the rapidly advancing field of 'omics research, there is an increasing demand for sophisticated bioinformatic tools to enable efficient and consistent data analysis. As biological datasets, particularly metabolomics, become larger and more complex, innovative strategies are essential for deciphering the intricate molecular and cellular networks.
Methods: We introduce a pioneering analytical approach that combines Principal Component Analysis (PCA) with Graphical Lasso (GLASSO).
The deuterated glucose insulin tolerance test: a new tool to delineate insulin-stimulated glucose uptake from suppression of endogenous glucose production.
Life Metab
February 2025
Department of Pathology, Microbiology, and Immunology, University of South Carolina-School of Medicine, Columbia, SC 29029, United States.
Graphical Abstract.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!