AI Article Synopsis
- Osteoporosis significantly impacts the Asia Pacific region, affecting 10-30% of women and up to 10% of men over 40, leading to a considerable number of fractures among older adults.
- A systematic review of literature from various countries (Australia, China, Hong Kong, Japan, Singapore, South Korea, and Taiwan) revealed inconsistent data quality and quantity on osteoporosis prevalence and fracture incidence, which typically increases with age.
- The findings underline the need for policymakers and healthcare systems in the Asia Pacific to improve prevention, diagnosis, and management of osteoporosis to alleviate healthcare costs and enhance patient outcomes.
Article Abstract
Unlabelled: Robust data on osteoporosis in the Asia Pacific region could improve healthcare decision-making. Osteoporosis affects 10-30% of women aged 40 + , and up to 10% of men in 7 developed economies in Asia Pacific. Fractures affect 500-1000 adults aged 50 + per 100,000 person-years. Policymakers and clinicians must address this problem.
Purpose: Osteoporosis and associated fractures result in considerable morbidity, loss of productivity, early mortality, and increased healthcare expenses. Many countries in the Asia Pacific (AP) region, especially middle- and higher-income economies, are faced with aging and increasingly sedentary populations. It is critical to consolidate and analyze the available information on the prevalence and incidence of the disease in these countries.
Methods: We systematically reviewed articles and gray literature for Australia, China, Hong Kong, Japan, Singapore, South Korea, and Taiwan. We searched PubMed, ScienceDirect, JSTOR, Cochrane, Google Scholar, and other databases for data published 2009-2018. We included articles with prevalence or incidence estimates for adults with osteoporosis or related fractures.
Results: All locations had data available, but of widely varying quantity and quality. Most estimates for osteoporosis prevalence ranged from 10 to 30% for women ages 40 and older, and up to 10% for men. Osteoporotic fracture incidence typically ranged between 500 and 1000 per 100,000 person-years among adults aged 50 and older. Both outcomes typically increased with age and were more common among women.
Conclusion: Osteoporosis and associated fractures affect significant portions of the adult population in developed economies in the AP region. Governments and healthcare systems must consider how best to prevent and diagnose osteoporosis, and manage affected individuals, to reduce healthcare costs and mortality associated with fractures.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202996 | PMC |
| http://dx.doi.org/10.1007/s00198-022-06657-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Treatment modification after second-line failure among people living with HIV in the Asia-Pacific.
Antivir Ther
May 2022
The Kirby Institute, UNSW Sydney, Sydney, NSW, Australia.
Background: The World Health Organization recommends continuation with the failing second-line regimen if third-line option is not available. We investigated treatment outcomes among people living with HIV in Asia who continued with failing second-line regimens compared with those who had treatment modifications after failure.
Methods: Treatment modification was defined as a change of two antiretrovirals, a drug class change or treatment interruption (TI), all for >14 days.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!