AI Article Synopsis

  • VT non-inducibility after radiofrequency (RF) ablation is generally linked to a lower chance of ventricular tachycardia (VT) recurrence, but its routine use as an endpoint is debated.
  • A study analyzed 62 patients who did not achieve VT non-inducibility post-ablation, finding that 35% experienced VT recurrences over two years.
  • Key factors influencing lower VT recurrence included a left ventricular ejection fraction (LVEF) of 35% or higher and the successful elimination of clinical VT during the procedure.

Article Abstract

Background: Ventricular tachycardia (VT) non-inducibility at the end of ablation is associated with a less likely VT recurrence. However, it is not clear whether we should use VT non-inducibility as a routine end point of VT ablation. The aim of this study was to evaluate VT recurrence in patients in whom VT non-inducibility was not achieved at the end of the radiofrequency (RF) ablation and the factors attributing to the VT recurrence.

Methods: We analyzed that 62 patients in whom VT non-inducibility was not achieved at the end of the RF ablation were studied.

Results: Over 2 years, 22 (35%) of the cases had VT recurrences. A multivariate analysis showed that an LVEF ≥35% (HR: 0.19; 95% CI: 0.06-0.49;  < .01) and elimination of the clinical VT as an acute ablation efficacy (HR: 0.23; 95% CI: 0.04-0.81;  = .02) were independent predictors of fewer VT recurrences. RF ablation was associated with a 91.1% reduction in VT episodes.

Conclusion: Even if VT non-inducibility was not achieved, patients with an LVEF ≥35% or in whom the clinical VT could be eliminated might be prevented from having VT recurrences. The validity of the VT non-inducibility of any VT should be evaluated considering each patient's background and the results of the procedure.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885314PMC
http://dx.doi.org/10.1002/joa3.12796DOI Listing

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