AI Article Synopsis

  • An 83-year-old man with advanced gastric cancer experienced melena and weight loss, leading to a diagnosis of pyloric stenosis and subsequent surgery.
  • Despite early recovery post-surgery, he developed severe dysphagia (difficulty swallowing) by POD6, with extensive tests showing no clear cause.
  • The dysphagia was ultimately linked to hypophosphatemia, which improved with nutritional intervention, highlighting a rare case where low phosphate levels affected swallowing in a cancer patient.

Article Abstract

An 83-year-old man presented with melena and weight loss. Upper gastrointestinal endoscopy showed type 3 advanced gastric cancer with pyloric stenosis. Surgical findings revealed numerous peritoneal dissemination, then gastro-jejunum anastomosis was performed. The oral diet was resumed on POD4, however severe dysphagia occurred immediately on POD6. There were no specific findings on MRI/MRA and nasal endoscopy. Serum antibodies related to neuromuscular diseases and connective tissue diseases were also negative. Despite the rehabilitation, the dysphagia remained. Before total parenteral nutrition on POD16, hypophosphatemia was discovered(1.4 mg/dL). His dysphagia disappeared with the improvement in the serum phosphate level. Hypophosphatemia might be caused by an inadequate intake as urine phosphate, serum calcium and serum PTH levels were normal. We present a recent case of severe dysphagia due to hypophosphatemia in a patient with peritoneal dissemination of gastric cancer.

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