Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among persons 71-80 years of age. Low antibody levels in 31.5% of this population indicates that addressing their vaccination should be a priority.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973709PMC
http://dx.doi.org/10.3201/eid2903.221231DOI Listing

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