Prcis: COVID-19 underlines the importance of telemedical diagnostics. The smartphone-based campimetry (Sb-C) is a newly developed digital application allowing visual field testing using a head-mounted device and a smartphone. It enables visual field screening remotely from a clinic.
Background: Sb-C is a newly developed tool for functional ophthalmic diagnosis. This study aimed to examine the comparability of the Sb-C and Octopus 900 to ensure ophthalmological care in times of social distancing.
Methods: Total 93 eyes were included in the study. After an ophthalmological examination, the visual field was tested by the Octopus program G1 and by the smartphone-based campimeter. The Sb-C was performed using VR glasses and an iPhone 6. The software Sb-C was downloaded and installed as SmartCampiTracker app and is examining the 30-degree visual field with 59 test positions corresponding to the G pattern of Octopus G1. Sensitivities were recorded and saved on the app. In addition, test-retest reliability was tested on 6 ophthalmologically healthy participants.
Results: The group comprised 48 women and 45 men (mean age: 62.52±12.2 y) including 19 controls, 17 patients with ocular hypertension, 11 preperimetric glaucomas, and 46 perimetric glaucomas. The mean sensitivity (MS) of all points of G1 perimetry was 23.13 dB (95% CI, 22.08-24.18). The MS of the Sb-C was 21.23 dB (95% CI, 20.37-22.08). The correlation between the mean MS measured by G1 perimetry and the Sb-C was strong ( r =0.815, P <0.05). The test-retest reliability showed a correlation of r =0.591 ( P <0.05) .
Conclusions: With some technical adjustments, the Sb-C shows promise for screening glaucoma and monitoring disease progression remotely from an ophthalmologic clinic.
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http://dx.doi.org/10.1097/IJG.0000000000002153 | DOI Listing |
Introduction: Mu-opioid receptors (MORs) are G-coupled protein receptors with a high affinity for both endogenous and exogenous opioids. MORs are widely expressed in the central nervous system (CNS), peripheral organs, and the immune system. They mediate pain and reward and have been implicated in the pathophysiology of opioid, cocaine, and other substance use disorders.
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Department of Radiology, The First Affiliated Hospital of Huzhou University, Huzhou, Zhejiang, People's Republic of China.
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January 2025
Department of Neurology, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Wenzhou, China.
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December 2025
School of Systems Science, Beijing Normal University, Beijing, 100875 China.
Hippocampus in the mammalian brain supports navigation by building a cognitive map of the environment. However, only a few studies have investigated cognitive maps in large-scale arenas. To reveal the computational mechanisms underlying the formation of cognitive maps in large-scale environments, we propose a neural network model of the entorhinal-hippocampal neural circuit that integrates both spatial and non-spatial information.
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Image Processing Laboratory, University of Valencia, Valencia, Spain.
In recent years, substantial strides have been made in the field of visual image reconstruction, particularly in its capacity to generate high-quality visual representations from human brain activity while considering semantic information. This advancement not only enables the recreation of visual content but also provides valuable insights into the intricate processes occurring within high-order functional brain regions, contributing to a deeper understanding of brain function. However, considering fusion semantics in reconstructing visual images from brain activity involves semantic-to-image guide reconstruction and may ignore underlying neural computational mechanisms, which does not represent true reconstruction from brain activity.
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