Background: In traumatic hemorrhage, hybrid operating rooms offer near simultaneous performance of endovascular and open techniques, with correlations to earlier hemorrhage control, fewer transfusions, and possible decreased mortality. However, hybrid operating rooms are resource intensive. This study quantifies and describes a single-center experience with the complications, cost-utility, and value of a dedicated trauma hybrid operating room.
Methods: This retrospective cohort study evaluated 292 consecutive adult trauma patients who underwent immediate (<4 hours) operative intervention at a Level I trauma center. A total of 106 patients treated before the construction of a hybrid operating room served as historical controls to the 186 patients treated thereafter. Demographics, hemorrhage-control procedures, and financial data as well as postoperative complications and outcomes were collected via electronic medical records. Value and incremental cost-utility ratio were calculated.
Results: Demographics and severity of illness were similar between cohorts. Resuscitative endovascular occlusion of the aorta was more frequently used in the hybrid operating room. Hemorrhage control occurred faster (60 vs. 49 minutes, p = 0.005) and, in the 4- to 24-hour postadmission period, required less red blood cell (mean, 1.0 vs. 0 U, p = 0.001) and plasma (mean, 1.0 vs. 0 U, p < 0.001) transfusions. Complications were similar except for a significant decrease in pneumonia (7% vs. 4%, p = 0.008). Severe complications (Clavien-Dindo classification, ≥3) were similar. Across the patient admission, costs were not significantly different ($50,023 vs. $54,740, p = 0.637). There was no change in overall value (1.00 vs. 1.07, p = 0.778).
Conclusion: The conversion of our standard trauma operating room to an endovascular hybrid operating room provided measurable improvements in hemorrhage control, red blood cell and plasma transfusions, and postoperative pneumonia without significant increase in cost. Value was unchanged.
Level Of Evidence: Economic/Value-Based Evaluations; Level III.
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http://dx.doi.org/10.1097/TA.0000000000003873 | DOI Listing |
Nature
January 2025
Institute of Physics, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.
The integrated frequency comb generator based on Kerr parametric oscillation has led to chip-scale, gigahertz-spaced combs with new applications spanning hyperscale telecommunications, low-noise microwave synthesis, light detection and ranging, and astrophysical spectrometer calibration. Recent progress in lithium niobate (LiNbO) photonic integrated circuits (PICs) has resulted in chip-scale, electro-optic (EO) frequency combs, offering precise comb-line positioning and simple operation without relying on the formation of dissipative Kerr solitons. However, current integrated EO combs face limited spectral coverage due to the large microwave power required to drive the non-resonant capacitive electrodes and the strong intrinsic birefringence of LiNbO.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Trauma Surgery, Jeju Regional Trauma Center, Cheju Halla General Hospital, 65 Doryeong-ro, Jeju, Jeju Special Self-Governing Province, 63127, Republic of Korea.
Traumatic intra-abdominal hemorrhage contributes to mortality in patients with trauma. However, initiating an emergent laparotomy in the operating room (OR) as a standard treatment can sometimes be time-consuming. To overcome this issue, laparotomy is performed in the emergency room (ER) in some institutions.
View Article and Find Full Text PDFNat Commun
January 2025
Haihe Laboratory of Sustainable Chemical Transformations, Tianjin, China.
Hydroxide exchange membrane (HEM) water electrolysis is promising for green hydrogen production due to its low cost and excellent performance. However, HEM often has insufficient stability in strong alkaline solutions, particularly under in-situ electrolysis operation conditions, hindering its commercialization. In this study, we discover that the in-situ stability of HEM is primarily impaired by the locally accumulated heat in HEM due to its low thermal conductivity.
View Article and Find Full Text PDFInt J Hyperthermia
December 2025
Department of Mechanical Engineering, Brigham Young University, Provo, UT, USA.
Purpose: In magnetic resonance-guided focused ultrasound (MRgFUS) breast therapies, the focal location must be characterized to guide successful treatment. Focal characterization is difficult because heterogeneous breast tissues introduce phase aberrations that blur and shift the focus and traditional guidance methods do not work in adipose tissues. The purpose of this work is to evaluate numerical simulations of MRgFUS that predict the focal location.
View Article and Find Full Text PDFJ Thorac Cardiovasc Surg
January 2025
McGill University Health Center, Faculty of Medicine, McGill University, Division of Cardiac Surgery, Department of Surgery, Montreal, Quebec, Canada.
Objective(s): We conduct a comparative study that employs the use of multiple dynamic deep learning algorithms to develop predictive models with video-based echocardiographic images using sample size determination as a key variable to assess optimal performance metrics.
Methods: Our study compares performance of 3D convolutional neural networks, video vision transformers, and hybrid convolutional neural networks and Long Short-Term Memory models within both supervised and semi-supervised domains using variable sample sizes.
Results: For supervised learning, the ResNet3D model achieved the lowest Mean Absolute Error (MAE) and Root Mean Square Error (RMSE) across all training set sizes (200, 400, and 800-video datasets), with the best performance observed on the 800-video training set (MAE: 7.
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