A 3-year-old boy presented with bluish patch and scattered blue spots on the left side of his face. After several sessions of laser treatment, the azury patch in the periorbital area became even darker. Histopathology showed many bipolar, pigment-laden dendritic cells scattered in the papillary and upper reticular dermis. Immunohistochemically, these cells were positive for S100, SOX-10, melan-A, P16, and HMB-45. The positive rate of Ki-67 was less than 5%. Finally, the lesion was diagnosed with nevus of Ota concurrent with common blue nevus. Therefore, for cases of the nevus of Ota with poor response to laser treatment, the possible coexisting diseases should be suspected.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.24920/004092 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Iris changes and pupillometry in Nevus of Ota.
Clin Exp Optom
December 2024
Department of Ophthalmology, Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India.
A Rare Case of Episcleral Melanoma with GNAQ Mutation Arising from Nevus of Ota.
Ophthalmology
December 2024
Department of Ophthalmology, Columbia University Irving Medical Center, New York, New York.
Wilson's Disease and Nevus of Ota in a Child: A Case Report.
Case Rep Ophthalmol
October 2024
Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
Article Synopsis
- Wilson's disease is a rare genetic disorder that affects copper metabolism and can cause specific eye problems, including Kayser-Fleischer rings and cataracts.
- A 10-year-old girl diagnosed with Wilson's disease also showed signs of nevus of Ota, which is hyperpigmentation around the eye.
- This case is notable as it is the first documented instance of nevus of Ota occurring in a child with Wilson's disease, and the patient currently has good vision and no symptoms.
Overlapping large facial nevus spilus and nevus of Ota: A case report diagnosed with dermoscopy and reflectance confocal microscopy.
Photodiagnosis Photodyn Ther
October 2024
Department of Dermatology, Air Force Medical Center, PLA, No.30 Fucheng Road, Beijing 100142, PR China. Electronic address:
Article Synopsis
- A 25-year-old woman presented with a large facial hyperpigmentation that began as a blue-brown patch at one month old and progressively enlarged, covering the entire right side of her face.
- Diagnosis involved dermoscopic and confocal microscopy exams, revealing overlapping conditions of nevus spilus and nevus of Ota, with no signs of cancer.
- Successful treatment was achieved with a Q-switched alexandrite laser, demonstrating the importance of advanced imaging techniques in diagnosing and managing rare facial pigmentation disorders.
Teaching NeuroImage: Meningeal Melanoma Associated With Blue Nevi and Nevi of Ota.
Neurology
November 2024
From the Departments of Radiology (S.M., L.F.F.), and Pathology (O.L.A.N., S.J.C.), University of Iowa Hospitals and Clinics, Iowa City.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!