Efficacy of adenotonsillectomy in the treatment of obstructive apnea in children: A 2-year follow-up.

Int J Pediatr Otorhinolaryngol

Universidade Federal de São Paulo, Rua Botucatu, 862 - Vila Clementino, São Paulo, SP, 04023-062, Brazil. Electronic address:

Published: March 2023

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http://dx.doi.org/10.1016/j.ijporl.2023.111462DOI Listing

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Article Synopsis
  • Obstructive sleep apnea (OSA) involves partial or complete airway obstruction during sleep, leading to poor sleep quality and health issues, particularly in children.
  • A study of 100 kids aged 4-12 assessed the severity of OSA and the effectiveness of surgical treatment, alongside comprehensive medical evaluations.
  • Findings showed that medical treatments, including intranasal steroids, significantly improved symptoms of mild OSA, as reflected in better parental sleep questionnaires and reduced Apnoea/Hypopnoea Index scores.
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Adenotonsillectomy Versus Watchful Waiting for Children with Obstructive Sleep Apnea Syndrome: A Systematic Review with Meta-Analysis.

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October 2024

1st Department of Otorhinolaryngology-Head and Neck Surgery, AHEPA University General Hospital, Aristotle University of Thessaloniki, Kiriakidi 1, Thessaloniki, 546 21 Greece.

Article Synopsis
  • This study investigates the effectiveness of adenotonsillectomy (ATE) versus watchful waiting in children with Obstructive Sleep Apnea Syndrome (OSAS), examining their clinical outcomes through a meta-analysis of various trials.
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Objective: We conducted a systematic review of randomized controlled trials (RCTs) to evaluate the efficacy of tranexamic acid (TXA) in reducing posttonsillectomy hemorrhage (PTH).

Data Sources: We searched MEDLINE, EMBASE, and CENTRAL for RCT comparing prophylactic TXA to control in patients undergoing tonsillectomy.

Review Methods: Per Preferred Reporting Items for Systematic Review and Meta-analysis guidelines, the databases were searched from date of inception through October 2023.

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Article Synopsis
  • Tonsillectomy and adenoidectomy (AT) are common ENT procedures for children, performed over 500,000 times a year in the U.S., and while generally safe, they carry risks like bleeding and pain.
  • Tranexamic acid (TXA) has been shown to reduce bleeding in various surgical settings, but its effectiveness and safety in pediatric AT haven't been thoroughly reviewed until now.
  • A systematic review of existing literature was conducted, analyzing eight studies involving 1,315 pediatric patients to assess the efficacy and safety of using TXA for reducing bleeding during tonsillectomy and adenoidectomy.
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Ciprofol in Children Undergoing Adenoidectomy and Adenotonsillectomy: A Retrospective Cohort Study.

Drug Des Devel Ther

September 2024

Department of Anesthesiology, Shenzhen University General Hospital, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.

Objective: Ciprofol is a novel anesthetic agent, its efficacy and safety had been verified and its clinical implementation has been expanded. However, the knowledge about ciprofol in children is meager. The aim of study is to evaluate the safety and effectiveness of ciprofol in general anesthesia in children undergoing adenoidectomy and adenotonsillectomy, compared with propofol.

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