Molecular dynamics simulations reveal a putative interaction surface for PUFAs on TM1 of ASICs that is not tightly conserved between isoforms.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929933 | PMC |
http://dx.doi.org/10.1085/jgp.202213307 | DOI Listing |
Phys Rev E
November 2024
Instituto de Fisica, Universidade de Sao Paulo, CEP 05315-970, Sao Paulo, SP, Brazil.
Inspired by studies of legislative-executive conflict in modern presidential democracies in South America, we present an agent-based statistical mechanics exploration of the collective, coordinated action of strategic political actors in the legislative chamber and the conditions that may result in premature changes in the executive officeholder, such as a president's impeachment or a motion of no confidence in a prime minister. The legislative actors are represented by information processing agents equipped with a neural network, and emit opinions about issues in the presidential agenda. We construct a Hamiltonian which is the sum of the costs for the agents to hold a specific set of political positions.
View Article and Find Full Text PDFCurr Opin Psychol
November 2024
University of Pennsylvania, Philadelphia, PA United States. Electronic address:
In our review, we explore two different flavors of social norms: strength and stability. These two fundamental features are crucial for understanding norm change and designing effective interventions. Strong norms, which significantly influence behavior and are widely adopted, and stable norms, which endure over time, are essential for group coordination and addressing collective challenges.
View Article and Find Full Text PDFDisaster Med Public Health Prep
December 2024
School of International Affairs and Public Administration, Ocean University of China, Qingdao, China.
Increasing transboundary crises necessitate the development of crisis management capabilities that transcend boundaries. In such situations, inter-governmental and cross-functional collaboration has become a common practice to address the complexities of governance challenges. This study employs Social Network Analysis to examine the structure, function, and evolution of policy collaboration networks in China in response to COVID-19 and SARS.
View Article and Find Full Text PDFMil Med
November 2024
Department of Pediatrics, Pediatric Sedation Unit, Walter Reed National Military Medical Center, Bethesda, MD 20889, USA.
Introduction: Nitrous oxide (N2O) is commonly used in pediatric procedural sedation. It is an attractive option to facilitate intravenous line placement, as it does not extend sedation recovery from subsequently administered agents. Although debate exists regarding health consequences of occupational exposure now that scavenging of exhaled gases is common, cooperation of pediatric patients to maximize engineering controls is not guaranteed and can contribute to repeated exposure over the course of a clinician's career.
View Article and Find Full Text PDFMacromol Rapid Commun
November 2024
Faculty of Science and Letters, Department of Chemistry, Soft Materials Research Laboratory, Istanbul Technical University, Maslak, Istanbul, 34469, Turkey.
Weakly anionic semi-interpenetrating polymer networks (semi-IPNs), comprised of copolymer poly(N-isopropylacrylamide-co-methacrylic acid) P(NIPA-MA) and linear poly(acrylamide) (LPA) chains as macromolecular crowding agent, are designed to evaluate pH-induced swelling and elasticity. Uniaxial compression testing after swelling in various pH-conditions is used to analyze the compressive elasticity as a function of swelling pH and LPA-content. The swelling of P(NIPA-MA)/LPA semi-IPNs is strongly pH-dependent due to MA units incorporated into the copolymer network which already exhibits temperature-sensitivity by presence of PNIPA counterpart.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!