Milkfish () belongs to the family Chanidae and it is a potential candidate species for aquaculture with the best biological characteristics. This study investigates the genetic diversity and population structure of . along the Indian coast using cytochrome b (cyt b) sequences of mitochondrial DNA (mtDNA). A total of 90 samples collected from five different locations across the Indian coast were sequenced for analysis using cyt b. The sequencing of a 1100-bp cyt b mtDNA fragment revealed the presence of 38 haplotypes with a haplotype diversity value of 0.835 and a nucleotide diversity value of 0.00400. The variation within and among populations accounted for about 97.33% and 2.67%, respectively. The fixation index analysis indicated that there is no significant genetic divergence among the populations from different geographical areas. Neighbour-joining tree analysis of the haplotype data showed no distinct patterns of phylogeographic structure. Results from this study indicated that there is a lack of genetic divergence between the populations of . along the Indian coast. The haplotype network showed star-like geneology which indicated the demographic expansion of the . population in these locations. The recent demographic expansion of the . population was also supported by the results of Tajima's statistics. Results from this study can be used for planning effective strategies for the conservation and management of the . population in the wild.
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R Soc Open Sci
January 2025
National Centre for Coastal Research (NCCR), Ministry of Earth Sciences (MoES), Chennai, India.
Tsunamis are massive waves generated by sudden water displacement on the ocean surface, causing devastation as they sweep across the coastlines, posing a global threat. The aftermath of the 2004 Indian Ocean tsunami led to the establishment of the Indian Tsunami Early Warning System (ITEWS). Predicting real-time tsunami heights and the resulting coastal inundation is crucial in ITEWS to safeguard the coastal communities.
View Article and Find Full Text PDFACS Infect Dis
January 2025
Pharmaceutical Chemistry Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani Campus, Pilani, Vidya Vihar 333031, (RJ) India.
Antimicrobial drug resistance is a significant global health challenge, causing hundreds of thousands of deaths annually and severely impacting healthcare systems worldwide. Several reported antimicrobial compounds have a guanidine motif, as the positive charge on guanidine promotes cell lysis. Therefore, pyrrole- and indole-based allylidene hydrazine carboximidamide derivatives with guanidine motifs are proposed as antimicrobial agents that mimic cationic antimicrobial peptides (CAMPs).
View Article and Find Full Text PDFSci Total Environ
January 2025
Department of Marine Sciences, Berhampur University, Bhanja Bihar 760007, India.
The Indian coast has been experiencing an increase in algal bloom events over the decades. Owing to the regional and seasonal dynamics of algal biomass (proxy: chlorophyll-a, hereafter chl-a), a multitude of thresholds of chl-a has been defined for different parts of the global seas to determine algal bloom conditions. However, no such clear definition is given for the Indian coastal waters.
View Article and Find Full Text PDFRSC Med Chem
December 2024
Pharmaceutical Chemistry Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Sciences Pilani Pilani Campus, Vidya Vihar Pilani 333031 RJ India +91 1596 244183 +91 1596 255 506.
Alzheimer's disease (AD) is a complex, incurable neurological condition characterized by cognitive decline, cholinergic neuron reduction, and neuronal loss. Its exact pathology remains uncertain, but multiple treatment hypotheses have emerged. The current treatments, single or combined, alleviate only symptoms and struggle to manage AD due to its multifaceted pathology.
View Article and Find Full Text PDFSci Rep
January 2025
Marine Biotechnology Fish Nutrition and Health Division, ICAR-Central Marine Fisheries Research Institute, Ernakulam North P O, Kochi, Kerala, 682018, India.
The Indian scad, Decapterus russelli is one of the most exploited pelagic resources of India. Population genetic analyses using mitochondrial and nuclear markers indicated a lack of genetic structuring among populations from Indian waters. As this species is highly migratory, it is also important to establish the environmental influence on its population structure.
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