AI Article Synopsis

  • Subcorneal pustular dermatosis (SPD) and annular pustular psoriasis (APP) are rare skin conditions in children that are challenging to tell apart.
  • A 10-year-old boy had a long history of red, scaly, ring-shaped patches with pustules, initially diagnosed as SPD, but his treatment and biopsy results pointed to APP.
  • After starting treatment with adalimumab, the boy completely recovered, highlighting the similarities between SPD and APP and suggesting they might be variations of the same disease.

Article Abstract

Subcorneal pustular dermatosis (SPD) and annular pustular psoriasis (APP) are very rare in childhood and difficult to differentiate both clinically and histopathologically. We report the case of a 10-year-old male with a 9-year history of erythematous scaly annular plaques with scattered pustules on the trunk. Although initially diagnosed as SPD, a lack of response to dapsone, presence of spongiosis on histology, and early age of disease onset led to consideration of APP. The patient was subsequently treated with adalimumab 80 mg weekly and completely cleared. This case illustrates the overlapping features of SPD and APP and suggests that the two disorders may represent a spectrum of the same disease.

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Source
http://dx.doi.org/10.1111/pde.15251DOI Listing

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