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Innate Immunity and Phenoptosis. | LitMetric

Innate Immunity and Phenoptosis.

Biochemistry (Mosc)

Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia.

Published: December 2022

AI Article Synopsis

Article Abstract

The hypothesis is proposed that activation of innate immunity is the primary mechanism of phenoptosis (programmed death of an organism). In support of the hypothesis, we discuss (i) the data on active release of signaling molecules from the cell producing excessive inflammation; (ii) the data on contribution of mitochondrial production of reactive oxygen species to immune response.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839199PMC
http://dx.doi.org/10.1134/S0006297922120185DOI Listing

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