Approximately 12% of histone H2B molecules in mammalian brain contain a modification wherein Asp25 is present as the D-enantiomer, and is mostly linked to Gly26 via the side-chain carboxyl. Here we (1) demonstrate the high specificity of a polyclonal antibody to this modification, and (2) use this Ab to demonstrate that this modification is enriched in brain relative to liver, thymus, and HeLa cells.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140013 | PMC |
| http://dx.doi.org/10.1007/s00726-023-03242-z | DOI Listing |
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