Hypercalcemic crisis due to severe decompensated hypercalcemia represents a life-threatening medical emergency leading to renal failure and altered mental status. Hypercalcemic crisis most commonly results from hypercalcemia of malignancy, undiagnosed primary hyperparathyroidism, granulomatous diseases, and medication-induced hypercalcemia. Commonly prescribed medications like thiazide diuretics, lithium therapy, and teriparatide are among the medications known to cause hypercalcemia. Here, we describe a case of the hypercalcemic crisis caused by excessive calcium carbonate ingestion emphasizing physicians to be aware of this potentially life-threatening adverse effect of a widely available over-the-counter acid reflux medication and educate patients regarding the same.
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http://dx.doi.org/10.7759/cureus.32913 | DOI Listing |
Cureus
October 2024
Department of Nutrition and Metabolism, Tokushima University Graduate School, Tokushima, JPN.
J Med Case Rep
November 2024
Department of Endocrinology and Medicine, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands.
Cureus
October 2024
Department of Endocrinology Diabetes Medicine, Samatvam Diabetes Endocrinology and Medical Center Samatvam: Science and Research for Human Welfare Trust, Bangalore, IND.
Parathyroid carcinoma (PC) is a rare malignancy. In January 2022, a 41-year-old woman presented with weight loss, proximal muscle weakness, and bone pain. She was diagnosed with severe hypercalcemia with serum calcium of 15.
View Article and Find Full Text PDFJCEM Case Rep
October 2024
Department of Intensive Care Medicine, University Teaching and Research Hospital Lucerne, 6000 Lucerne, Switzerland.
Metastatic calcifications are a rare but potentially fatal complication of primary hyperparathyroidism (PHPT). In this case, a 76-year-old man with a previously asymptomatic PHPT developed a hypercalcemic crisis with severe pancreatitis following elective urologic surgery. Despite initial treatment focused on pancreatitis and subsequent organ failure, hypercalcemia persisted, leading to rapid progressive metastatic calcifications in multiple organs.
View Article and Find Full Text PDFInt J Endocrinol
August 2024
Department of Endocrinology The First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Objective: This study aimed to analyse the etiology and clinical characteristics of hypercalcemic crisis in a large cohort of Chinese patients and summarised our clinical experience in the management of this serious endocrinological emergency.
Methods: This was a retrospective analysis of a cohort of patients with hypercalcemic crisis hospitalized in the First Medical Center of Chinese PLA General Hospital between January 2009 and March 2024. The general data, clinical manifestations, etiology, photographic examination, emergency treatment, etiological treatment, and prognosis were analysed.
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