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SMARCB1(INI-1)-deficient sinonasal carcinoma is a rare, poorly differentiated neoplasm with a poor prognosis. Though historically most were identified as sinonasal undifferentiated carcinoma, we now understand it to be a distinct entity. There is currently a general consensus supporting multimodal therapy, though the optimal sequence of surgery, chemotherapy, and radiation has yet to be defined.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883109PMC
http://dx.doi.org/10.1055/a-1996-1283DOI Listing

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