A new Zn(II) coordination polymer based on -phthalato (Phth) and 2-aminopyridine (2-Ampy) viz. {[Zn(2Ampy)(Phth)]∙(HO)]} () has been synthesized at room temperature and characterized by elemental analyses, electronic spectroscopy, FTIR spectroscopy, thermal analysis (TGA/DSC), powder Xray diffraction (PXRD) and single crystal Xray diffraction. The basic trimeric units of form a polymeric chain by N-H⋯O and π⋯π interactions. These polymeric chains interconnect through various non-covalent interactions in two perpendicular directions to ultimately give rise to a 3D architecture of . The interesting non-covalent interactions in , contributing to its stability in the solid state are studied by Hirshfeld surface analysis and other different theoretical tools. Molecular docking study of is performed against six different proteins of SARS-CoV-2. The drug potential of the synthesized compound is evaluated by ADMET calculations.
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| http://dx.doi.org/10.1016/j.poly.2023.116304 | DOI Listing |
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