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Lipid Changes 10-15 Years After Roux-en-Y Gastric Bypass: A Prospective Observational Study.
Obes Surg
January 2025
Medical Department, Ålesund Hospital, Møre Og Romsdal Hospital Trust, 6026, Ålesund, Norway.
Background: Several studies have documented a beneficial short-term effect on lipid profile after Roux-en-Y gastric bypass (RYGB), but there is limited data on long-term changes.
Objectives: To describe long-term (> 10 years) changes in lipid profile after RYGB and to explore the relationship of lipid changes to changes in weight and baseline and demographic parameters.
Methods: The BAROBS study is a prospective observational study post RYGB conducted at three different hospitals.
Gastric cancer in Ukraine: epidemiologic data and its nosological structure between 2003 and 2020.
Prz Gastroenterol
February 2024
Department of Social Medicine, Public Health and Health Care Management, Dnipro State Medical University, Dnipro, Ukraine.
Introduction: Gastric cancer is one of the world's leading causes of death due to oncological diseases. Gastric cancer comprises a diverse group of diseases that includes several oncological units.
Aim: To analyse the nosological structure of epidemiological data related to gastric cancer in Ukraine and compare it with global trends from 2003 to 2020.
Prevalence of medical conditions or comorbidities influencing first-line therapy in unresectable hepatocellular carcinoma in the United States.
Future Oncol
January 2025
Cardinal Health, Dublin, OH, USA.
Introduction: Given treatment landscape changes, understanding the prevalence of medical conditions/comorbidities influencing real-world unresectable hepatocellular carcinoma (uHCC) treatment decisions is key for improving outcomes.
Patients And Methods: In a retrospective chart review, physicians abstracted data from uHCC patients initiating first-line treatment (1L) between June 2020 and April 2022. Frequencies of medical conditions/comorbidities at 1L initiation were reported.
Molecular-targeted Therapy for Precision Medicine in Gastrointestinal Cancer: Advancement in Cancer Targeting Strategies.
Curr Cancer Drug Targets
January 2025
Department of Pharmacology, Maharana Pratap College of Pharmacy kanpur Uttar Pradesh, 209217, India.
Gastrointestinal (GI) cancer represent significant health challenges, affecting the digestive system with often subtle symptoms that can delay diagnosis. GI cancers account for a higher global mortality rate than any other cancer, largely due to the limited availability of highly effective treatment options." Due to next-generation sequencing and new preclinical model tools, that we have learned more regarding its pathophysiology and molecular changes.
View Article and Find Full Text PDFReflecting on the impact of the COVID pandemic on patient management and its subsequent influence on long-term outcomes: a case-control study in the field of esophago-gastric cancer.
World J Surg Oncol
January 2025
Department of Oesophago-Gastric & Bariatric Surgery, Salford Care Organisation, Northern Care Alliance NHS Foundation Trust, Salford Royal Hospital, Manchester, UK.
Background: The delivery of cancer services changed significantly during the COVID-19 pandemic. This study aimed to describe changes in presentations, assess the change in recommendations by the MDT during the pandemic, and describe the subsequent long-term impact of these changes on survival rates in patients with EG cancer.
Methods: A retrospective cohort study was designed comparing three patient groups of those referred to EG MDT in the same 6-month period pre-pandemic (PP;2019) during the initial phase of the pandemic (P1;2020) and the year after the initial phase (P2;2021).
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