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Atherosclerosis is the leading cause of mortality globally. RBC-platelet hybrid membrane-coated nanoparticles ([RBC-P]NPs), which biologically mimic platelets in vivo, display evidence of anti-atherosclerotic activity. The efficacy of a targeted RBC-platelet hybrid membrane-coated nanoparticles ([RBC-P]NP)-based approach was investigated as a primary preventive measure against atherosclerosis.
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Biodegradable materials are a next-generation invention for the treatment of congenital heart diseases. However, the corresponding technology used to develop ideal biomaterials still presents challenges. We previously reported the first biodegradable atrial septal defect (ASD) occluder made of poly-lactic acid (PLLA).
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Department of Macromolecular Science and Engineering, Graduate School of Science & Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan. Electronic address:
The latex agglutination test is employed to visualize antigen-antibody reactions through the aggregation of antibody-coated particles in the presence of an antigen. In the present study, we developed an ultrasound scattering technique to detect latex agglutination in an optically turbid media. However, the ultrasonic technique had less sensitivity to the dilute particle suspension than the optical techniques because of its wavelength.
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