AI Article Synopsis
- Recent research indicates that the genitourinary microbiome is important in the development and progression of urological tumors, particularly bladder cancer.
- The role of Bacille Calmette Guérin (BCG), a vaccine used in treating non-muscle invasive bladder cancer (NMIBC), is well-documented, but there is limited understanding of how it interacts with the genitourinary microbiome.
- This emerging field calls for more research to explore the microbiome's influence on bladder cancer diagnosis, recurrence prevention, and treatment options.
Article Abstract
Recent evidence suggests that the human genitourinary microbiome plays a significant role in mediating the development and progression of urological tumors, including bladder cancer (BC). Clinicians widely recognize the role of Bacille Calmette Guérin (BCG), an attenuated vaccine, in the management of intermediate- and high-risk NMIBC. However, compared to the large body of evidence on the gut microbiota and gastrointestinal tumors, limited information is available about the interaction between BC and the genitourinary microbiome. This is an expanding field that merits further investigation. Urologists will need to consider the potential impact of the microbiome in BC diagnosis, prevention of recurrence and progression, and treatment prospects in the future. This review highlights the approaches adopted for microbiome research and the findings and inadequacies of current research on BC.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871226 | PMC |
| http://dx.doi.org/10.1016/j.heliyon.2023.e13012 | DOI Listing |
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