A 26-year-old man in Australia who has sex with men had severe perianal ulceration, proctitis, and skin lesions develop. Testing revealed primary syphilis, mpox, and primary HIV infection. Recent publications have documented severe mpox associated with HIV infection. Disruption of mucosal integrity by mpox lesions could enable HIV transmission and vice versa.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973693PMC
http://dx.doi.org/10.3201/eid2903.221845DOI Listing

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