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Background: Cardioneuroablation (CNA) treats reflex syncope by ablating ganglionated plexi (GPs) either confined to the right (RA) or left atrium (LA), or accessible from both. We assessed whether GP ablation in one atrium affects parasympathetic modulation in the other and how ablation sequence (RA then LA, or vice-versa) impacts efficacy.

Methods: Two propensity-matched groups of patients with reflex syncope or functional bradycardia were analyzed.

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Article Synopsis
  • A young patient with neuromyelitis optica spectrum disorder experienced recurrent cardiac asystole and syncope following persistent hiccups, but successfully underwent cardioneuroablation (CNA) treatment, avoiding the need for a permanent pacemaker.
  • Previous cases of symptomatic bradycardia-arrhythmia related to area postrema syndrome (APS) showed a significant number required pacemaker implantation, highlighting the severity of the condition.
  • The findings suggest that CNA can effectively treat bradyarrhythmia associated with APS, and healthcare professionals should consider the potential link between these symptoms and APS in their clinical assessments.*
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Background: Patient's clinical characteristics, technical resources, center and operator volume, and operator experience and training are known variables impacting outcomes. Although international standards have been agreed to maximize the benefits of this therapy, regional and global differences still exist. Latin American information has not been updated in the last 10 years.

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Article Synopsis
  • Cardioneuroablation (CNA) is a therapy for conditions like vasovagal syncope, atrioventricular block, and sinus node dysfunction, but its effectiveness for patients over 50 is unclear.
  • In a study with 50 patients divided into two age groups (under 50 vs. 50 and above), there was no significant difference in survival rates without syncope or the need for pacemakers between the groups after a median follow-up of 17 months.
  • Older patients had lower heart rate post-procedure compared to younger patients, but both age groups showed similar improvements in quality of life and a decrease in heart rate variability.
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