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Background: Antibiomania is the manifestation of manic symptoms secondary to taking an antibiotic, which is a rare side effect. In these cases, the antibiotics most often incriminated are macrolides and quinolones, but to our knowledge, there are no published cases of antibiomania secondary to cotrimoxazole. Furthermore, we also provide an update of pharmacovigilance data concerning antibiomania through a search of the World Health Organization (WHO) database.
View Article and Find Full Text PDFGenome-based development and clinical evaluation of a customized LAMP panel to rapidly detect, quantify, and determine antibiotic sensitivity of Escherichia coli in native urine samples from urological patients.
Eur J Clin Microbiol Infect Dis
January 2025
Clinic for Urology, Pediatric Urology and Andrology, Justus-Liebig-University, Giessen, Germany.
Purpose: We designed and tested a point of care test panel to detect E.coli and antibiotic susceptibility in urine samples from patients at the point of care in the urological department. The aim of this approach is to facilitate choosing an appropriate antibiotic for urinary tract infections (UTI) at first presentation in the context of increasing antibiotic resistance in uropathogens worldwide.
View Article and Find Full Text PDFThe First Case of Endocarditis in Italy: Case Presentation and Systematic Literature Review.
Medicina (Kaunas)
December 2024
Infectious and Tropical Diseases Unit, Padua University Hospital, 35128 Padua, Italy.
Almost 25 years have now passed since the first identification of (). It can cause infections both in immunocompetent and immunocompromised hosts. However, it has been rarely described as an aetiology of infectious endocarditis.
View Article and Find Full Text PDFAdditional benefits of combined ceftriaxone and adipose-derived mesenchymal stem cells on revamping the outcomes in rodent after acute spinal infection.
J Mol Histol
January 2025
Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123 Dapi Rd. Niaosung Dist, Kaohsiung City, 83301, Taiwan.
Article Synopsis
- The study examined the effects of ceftriaxone and adipose-derived mesenchymal stem cells (ADMSCs) on protecting the spinal cord from acute spinal infection (ASI) in rats.
- Results showed that the combination treatment of ceftriaxone and ADMSCs led to significantly lower inflammatory markers and bacterial counts compared to the individual treatments, indicating better inflammation control and tissue preservation.
- By day 28, the combination therapy demonstrated superior results in protecting vertebral bone and spinal cord integrity compared to each treatment alone, suggesting a potential therapeutic strategy for ASI.
elimination of antimicrobials during ADVanced Organ Support hemodialysis.
Front Pharmacol
December 2024
ADVITOS GmbH, Munich, Germany.
Background: Acute kidney injury (AKI) requiring continuous renal replacement therapy is common in critically ill patients. The ADVanced Organ Support (ADVOS) system is a novel hemodialysis machine that uses albumin enriched dialysate which allows the removal of protein-bound toxins and drugs. To date, data on antimicrobial removal under ADVOS has not yet been reported.
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