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| http://dx.doi.org/10.1161/JAHA.122.028494 | DOI Listing |
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A chain mediation model reveals the association between depression and cognitive function in the elderly.
Sci Rep
December 2024
School of Humanities and Management, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
The purpose of this study was to explore the relationship between depression, cognitive function, social activities and activities of daily living ( ADL ), and verify whether social activities and ADL have a chain mediating effect between depression and cognitive function. Using the data of the fourth phase of the China Health and Retirement Longitudinal Study ( CHARLS ), 7547 elderly samples were studied. Correlation analysis and Bootstrap method were used to analyze the data to test whether social activities and ADL played a chain mediating role between depression and cognitive function in the elderly.
View Article and Find Full Text PDFMental health service users' experiences of everyday occupations while attending day centres during the transition into retirement age.
Scand J Occup Ther
January 2025
Department of Health Sciences, Mental Health, Activity and Participation (MAP), Lund University, Lund, Sweden.
Background: Existing research has shown that those ageing with severe mental illness face significant challenges in daily life. Attendance at community-based day centres (DCs) is offered to support daily structure and break isolation. However, little is known about the experiences of those receiving this type of support while transitioning into retirement age.
View Article and Find Full Text PDFThe necessity of validity diagnostics when drawing causal inferences from observational data: lessons from a multi-database evaluation of the risk of non-infectious uveitis among patients exposed to Remicade.
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Janssen Research & Development LLC, Global Epidemiology Organization, Raritan, NJ, USA.
Background: Autoimmune disorders have primary manifestations such as joint pain and bowel inflammation but can also have secondary manifestations such as non-infectious uveitis (NIU). A regulatory health authority raised concerns after receiving spontaneous reports for NIU following exposure to Remicade, a biologic therapy with multiple indications for which alternative therapies are available. In assessment of this clinical question, we applied validity diagnostics to support observational data causal inferences.
View Article and Find Full Text PDFGendered dimension of chronic pain patients with low and middle income: A text mining analysis.
PLoS One
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Iscte-University Institute of Lisbon, Centre for Social Research and Intervention (Cis-Iscte), Lisbon, Portugal.
Methods: This is a mixed-method study using individual interviews (duration between 40-60 minutes) of 181 CNCP patients (71% females) in a tertiary Pain Care Unit, and applying the text mining methodology. Incomes (low or middle) and gender roles (productive vs. reproductive)".
View Article and Find Full Text PDFAssociation between social engagement decline and cognitive function changes: mediating effect of depressive symptoms.
Aging Clin Exp Res
December 2024
Innovation Center of Nursing Research and Nursing Key Laboratory of Sichuan Province, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, 610041, PR China.
Background: Cognitive decline is a significant public health problem worldwide, but little is known about social engagement's impact on cognitive changes over time. This study aimed to explore the relationship between social engagement decline and cognitive function change in Chinese adults, and to analyze the effect of changes in depressive symptoms on this relationship.
Methods: Participants were selected from the China Health and Retirement Longitudinal Study.
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