Glomus jugulare tumors treatment by gamma knife radiosurgery: A single center study.

Pak J Med Sci

Prof. Dr. Abdul Sattar M. Hashim, PhD., M.D Neuro Surgery. Ex Prof JPMC, Medical Director, Neuro Spinal & Cancer Care Institute, Karachi, Pakistan.

Published: January 2023

Objective: Glomus jugulare tumor are benign vascular tumors and surgical resection is almost impossible. We have treated these tumors by Gamma knife radiosurgery and share our experience.

Methods: This study was conducted at the Neurospinal and Cancer Care Institute, Karachi from January 2010 to May 2020. Thirty-four patients with glomus jugulare tumors treated with gamma knife radiosurgery were included in the study. The comprehensive clinical and demographic characteristics of all patients were collected through a manually designed questionnaire. Computed tomography, digital subtraction angiography and magnetic resonance imaging were used to make the diagnosis. Data was incorporated and analyzed by SPSS version 26.

Results: A total of 34 patients were included in the study of which 16(47%) were males and 18(53%) were females with first follow up after 6-month up to two year clinical and radiological follow-up. The mean age of the patients was 42.5±13.5 with a minimum age of 20 years and maximum age of 65 years. The KPS scale was 2.09±0.45 and the volume of the tumor was 33.8±22.5 cm. The improvement was shown in 27 patients of which 14 were males and 13 were females showing insignificance post radiation change. Of all 34 patients, the outcome was recorded as 3(9%) for excellent, 22(64%) for good, 6(17%) for fair and 3(9%) were poor results.

Conclusions: Gamma Knife radiosurgery is a safe and effective primary therapy and salvage therapy for residual and recurrent cases of glomus jugulare and tympanicum tumors.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843021PMC
http://dx.doi.org/10.12669/pjms.39.1.6590DOI Listing

Publication Analysis

Top Keywords

glomus jugulare
16
gamma knife
16
knife radiosurgery
16
jugulare tumors
8
included study
8
age years
8
patients
6
tumors
5
glomus
4
tumors treatment
4

Similar Publications

Purpose: To compare the performance of the photon-counting detector (PCD)-CT versus a state-of-the-art energy-integrating detector (EID)-CT to identify segments of the inferior tympanic canaliculus (Jacobsons nerve) and the mastoid canaliculus (Arnolds nerve).

Materials & Methods: Patients were prospectively recruited to undergo temporal bone CT on both EID-CT (Siemens Somatom Force) and PCD-CT (Siemens NAEOTOM Alpha) scanners under an IRB-approved protocol. Three neuroradiologists reviewed cases by consensus comparing the ability to identify the proximal, mid, and distal segments of the inferior tympanic canaliculus/Jacobsons nerve and mastoid canaliculus/Arnolds nerve on each scanner using 5-point Likert scales (with 1 indicating EID is far superior to PCD, 3 indicating they are equivalent, and 5 indicating PCD is far superior to EID).

View Article and Find Full Text PDF
Article Synopsis
  • A carotid body tumor, or paraganglioma, is a rare tumor that usually occurs in the neck and is mostly benign, accounting for only 0.5% of all tumors.
  • A case study of a 22-year-old male revealed symptoms like swelling in the neck, hoarseness, and difficulty swallowing, leading to a diagnosis confirmed by ultrasound and MRI.
  • The primary treatment for carotid body tumors is surgical removal, and the patient's surgery was guided by the Shamblin classification to assess the tumor's resectability and reduce vascular complications.
View Article and Find Full Text PDF
Article Synopsis
  • A case study was done on a big tumor called giant glomus jugulare paraganglioma, which can cause hearing loss and ringing in the ears.
  • The tumor was successfully removed without hurting the patient's facial nerve, and there were no signs of the tumor coming back after 2 years.
  • This kind of tumor can be hard to recognize early on because it often shows different symptoms, making it rare to diagnose correctly at first.
View Article and Find Full Text PDF
Article Synopsis
  • Jugular paraganglioma is a type of tumor that grows slowly and is found near important blood vessels and nerves in the head.
  • This paper looks at new research about how these tumors work, how they can be treated with surgery and radiation, and what doctors need to know to help patients.
  • It aims to give helpful information for understanding, diagnosing, and treating these tumors better in the future.
View Article and Find Full Text PDF
Article Synopsis
  • The article reviews the use of internal carotid artery stenting in surgeries for glomus jugular paragangliomas to minimize the risk of artery injury during procedures.
  • It highlights a study involving 5 patients from 2018 to 2022 who underwent imaging assessments and successfully received stents before tumor removal surgeries.
  • Postoperative results showed that the stents remained patent and effective, emphasizing preoperative stenting as a safe strategy to protect the internal carotid artery during surgery.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!