More enduring formal youth mentoring relationships tend to be more effective, but our understanding of how such relationships develop and are sustained remains limited. This prospective, qualitative study examined the development of 67 one-to-one, community-based mentoring relationships over a 2-year period. Data included interviews with mentors, youth, and the youth's parent/guardian across multiple time-points and agency case notes. Five developmental trajectories were identified: (a) continued growth, (b) initial growth that plateaued, (c) initial growth followed by decline and then recovery, (d) initial growth followed by decline with no recovery, and (e) little to no growth or connection. Matches in the continued growth and recovery groups were more enduring and experienced by participants as meaningful connections. Factors that appeared to have contributed to these different trajectories were youth interest in the mentoring relationship, mentor empathy, flexibility, and commitment, and program support.
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http://dx.doi.org/10.1002/jcop.23006 | DOI Listing |
J Am Acad Orthop Surg Glob Res Rev
January 2025
Universidad Autónoma de Guadalajara, School of Medicine, Zapopan, Mexico.
Background: Physicians worldwide face the challenging task of improving patient satisfaction by reducing pain in injured patients. Currently, available therapeutic approaches provide only short-term relief of symptoms without addressing long-term satisfaction. This has led to exploring regenerative treatment options that can deliver better outcomes.
View Article and Find Full Text PDFAm J Physiol Cell Physiol
January 2025
Department of Anatomy, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan City 33302, Taiwan.
Hyperglycemia and hyperglycosuria, two primary characteristics of diabetes mellitus, may increase the risk of cancer initiation, particularly for bladder cancer. The effectiveness of metformin, a common antidiabetic agent, is determined by its ability to induce GDF15. However, the mechanism of the GDF15 in relation to glucose, which influences the tumor microenvironment in the human bladder, is not fully understood.
View Article and Find Full Text PDFJMIR Public Health Surveill
January 2025
Faculty of Human-Environment Studies, Kyushu University, Fukuoka, Japan.
Background: The effects of physical activity (PA) across different domains and intensities on depressive symptoms remain inconclusive. Incorporating the community-built environment (CBE) into longitudinal analyses of PA's impact on depressive symptoms is crucial.
Objective: This study aims to examine the effects of PA at different intensities-low-intensity PA (eg, walking activities) and moderate-to-vigorous-intensity PA (eg, activities requiring substantial effort and causing faster breathing or shortness of breath)-across leisure-time and occupational domains on depressive symptom trajectories among middle-aged and older adults.
Head Neck Pathol
January 2025
Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Purpose: Recurrent diffuse-type tenosynovial giant cell tumor: Clinical presentation, Diagnosis, and Management.
Background: Tenosynovial giant cell tumor (TGCT), is a neoplasm arising from synovial joints, bursae, or tendon sheaths. The initial clinical symptoms are vague and non-diagnostic.
Microbiol Spectr
January 2025
Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Unlabelled: Group A (GAS) is a major human pathogen that causes several invasive diseases including necrotizing fasciitis. The host coagulation cascade initiates fibrin clots to sequester bacteria to prevent dissemination into deeper tissues. GAS, especially skin-tropic bacterial strains, utilize specific virulence factors, plasminogen binding M-protein (PAM) and streptokinase (SK), to manipulate hemostasis and activate plasminogen to cause fibrinolysis and fibrin clot escape.
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