Considering the growing sense of ambivalence about the merits of the DSM, the time seems right for the re-evaluation of nosological attempts and efforts in the pre-DSM era. One example of these attempts is the CHAM system developed by the Dutch psychiatrist R.M. Silbermann (1932-1976). This system is intended as a simple classification with 20 "psychiatric states," which are classified based on the presence of one of 12 hierarchically arranged core symptoms or key characteristics, while all "hierarchically higher" symptoms are excluded without inference about the "hierarchically lower" symptoms. Its scientific evidence is, as yet, insufficiently substantiated. However, disqualifying the CHAM system as an outdated Dutch folklore is like throwing out the baby with the bathwater. The CHAM system emerges as clinically straightforward, didactically fruitful, and consistent with more modern initiatives in descriptive psychopathology. Studying pre-DSM attempts such as Silbermann's CHAM system can stimulate psychopathological thinking and serve as a source of inspiration for future phenomenological research in psychiatry.
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http://dx.doi.org/10.1159/000528831 | DOI Listing |
Cogn Neurodyn
December 2024
MathNeuro Team, Inria at Université Côte d'Azur, 2004 route des Lucioles-BP93, Sophia Antipolis, 06902 France.
Mixed affective states in bipolar disorder (BD) is a common psychiatric condition that occurs when symptoms of the two opposite poles coexist during an episode of mania or depression. A four-dimensional model by Goldbeter (Progr Biophys Mol Biol 105:119-127, 2011; Pharmacopsychiatry 46:S44-S52, 2013) rests upon the notion that manic and depressive symptoms are produced by two competing and auto-inhibited neural networks. Some of the rich dynamics that this model can produce, include complex rhythms formed by both small-amplitude (subthreshold) and large-amplitude (suprathreshold) oscillations and could correspond to mixed bipolar states.
View Article and Find Full Text PDFTop Curr Chem (Cham)
November 2024
Hangzhou Institute of Advanced Study, University of Chinese Academy of Sciences, 1 Sub-Lane Xiangshan, Hangzhou, 310024, China.
Plants (Basel)
October 2024
Postgraduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato 63105-00, Ceará, Brazil.
(1) Background: Cham is a Brazilian aromatic plant rich in phenolic compounds. In traditional medicine, its leaves are used to treat diseases of the Central Nervous System such as stress and anxiety. This study evaluates the capacity of the aqueous extract of as an anticonvulsant, anticholinesterase and antihemolytic agent.
View Article and Find Full Text PDFSensors (Basel)
October 2024
Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Phys Rev E
August 2024
Department of Aeronautics and Astronautics, Kyoto University, Kyoto-daigaku-katsura, Kyoto 615-8540, Japan.
Steady solutions of a single droplet or bubble in the van der Waals fluid are investigated on the basis of the kinetic model equation that has been recently proposed by Miyauchi et al. [Gas Dynamics with Applications in Industry and Life Sciences (Springer, Cham, 2023), pp. 19-39].
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