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| http://dx.doi.org/10.1148/radiol.223144 | DOI Listing |
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Analysis of the Belgian RTT workforce and estimation of workforce needs for the near future.
Radiography (Lond)
December 2024
Université Libre de Bruxelles (ULB), Brussels University Hospital, Jules Bordet Institute, Radiotherapy Department, Rue Meylemeersch 90, 1070 Bruxelles, Belgium.
Introduction: Radiation Therapists (RTTs) are crucial in delivering Radiotherapy (RT) to cancer patients. The advancements in RT technology and the increasing cancer incidence have heightened the demand for RTTs, necessitating strategic workforce planning at the national level. This study aims to identify and estimate current and future RTT workforce in Belgium.
View Article and Find Full Text PDFAmelioration of signaling deficits underlying metabolic shortfall in TREM2 human iPSC-derived microglia.
FEBS J
December 2024
Department of Neuroinflammation, UCL Queen Square Institute of Neurology, University College London, UK.
The microglial triggering receptor expressed on myeloid cells 2 (TREM2) is required for diverse microglia responses in neurodegeneration, including immunometabolic plasticity, phagocytosis, and survival. We previously identified that patient iPSC-derived microglia (iPS-Mg) harboring the Alzheimer's disease (AD) TREM2 hypomorph display several functional deficits linked to metabolism. To investigate whether these deficits are associated with disruptions in metabolite signaling, we generated common variant, TREM2 and TREM2 variant human iPS-Mg.
View Article and Find Full Text PDFParamedics providing end-of-life care: an online survey of practice and experiences.
BMC Palliat Care
December 2024
School of Health Sciences, University of Southampton, Southampton, UK.
Background: Global demand for care during the last year of life (end-of-life) is rising and with shortfalls in community healthcare services, paramedics are increasingly called on to deliver this. Despite this growing demand on the paramedic workforce, little large-scale or detailed empirical research has evaluated current practice and paramedic experiences of attending this patient group. Therefore, as part of a wider study evaluating paramedic delivery of end-of-life care, a large-scale survey in England describing paramedics' current practice and experiences providing end-of-life care was undertaken.
View Article and Find Full Text PDFNormal echocardiographic findings in healthy pregnant women: A narrative review of the literature.
Curr Probl Cardiol
December 2024
Cardiology Section, Internal Medicine Department, Universidad de Antioquia, Medellín, Colombia; Cardiopulmonary and Peripheral Vascular Service, Hospital San Vicente Fundación, Medellín, Colombia; Cardio-Obstetric Clinical Leader, Hospital San Vicente Fundación, Medellín, Colombia.
During pregnancy, significant physiological changes occur that result in cardiac remodeling and altered functional performance, though these are generally reversible postpartum. Pregnancy increases the cardiovascular system's demand, requiring substantial adaptations such as elevated cardiac output (CO), plasma volume, stroke volume (SV), and heart rate (HR), alongside a reduction in systemic vascular resistance (SVR) and mean arterial pressure. These adaptations, essential to meet the hemodynamic needs of both the mother and fetus, often differ from standard echocardiographic measurements used to evaluate cardiac function, making interpretation challenging.
View Article and Find Full Text PDFReturn on Investment of Preoperative Anemia Management Programs in Cardiac Surgery: An Advisory From the Society of Cardiovascular Anesthesiologists Clinical Practice Improvement Committee With Endorsement by the Society for the Advancement of Patient Blood Management.
Anesth Analg
November 2024
Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina.
Despite multiple recent guidelines recommending the diagnosis and treatment of anemia before elective cardiac surgery, few institutions have formal programs or methods in place to accomplish this. A major limitation is the perceived financial shortfall and the leadership buy-in required to undertake such an initiative. The purpose of this advisory from the Society of Cardiovascular Anesthesiologists (SCA) Clinical Practice Improvement Committee with endorsement by the Society for the Advancement of Patient Blood Management (SABM) is to provide an overview of preoperative anemia management programs with an emphasis on the associated financial implications.
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