Breakthrough of glycobiology in the 21st century.

Front Immunol

Institute of Clinical Electrocardiography, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.

Published: January 2023

AI Article Synopsis

  • Glycan-based therapies have gained significant traction in modern medicine since the 20th century, thanks in part to advancements in research and new tools for studying carbohydrates.
  • The emergence of glycomics, a new field focused on the study of glycans, offers exciting potential for understanding and treating complex diseases while enhancing diagnostic and therapeutic development.
  • This review highlights the recent progress that has elevated glycan-based therapies to a prominent position in medicine, showcasing the technologies that have driven these advancements as pivotal successes of the 21st century.

Article Abstract

As modern medicine began to emerge at the turn of the 20th century, glycan-based therapies advanced. DNA- and protein-centered therapies became widely available. The research and development of structurally defined carbohydrates have led to new tools and methods that have sparked interest in the therapeutic applications of glycans. One of the latest omics disciplines to emerge in the contemporary post-genomics age is glycomics. In addition, to providing hope for patients and people with different health conditions through a deeper understanding of the mechanisms of common complex diseases, this new specialty in system sciences has much to offer to communities involved in the development of diagnostics and therapeutics in medicine and life sciences.This review focuses on recent developments that have pushed glycan-based therapies into the spotlight in medicine and the technologies powering these initiatives, which we can take as the most significant success of the 21st century.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850147PMC
http://dx.doi.org/10.3389/fimmu.2022.1071360DOI Listing

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